| Literature DB >> 15889369 |
Brahm H Segal1, Lisa A Barnhart, Victoria L Anderson, Thomas J Walsh, Harry L Malech, Steven M Holland.
Abstract
Chronic granulomatous disease (CGD) is characterized by life-threatening bacterial and fungal infections. Treatment with posaconazole led to a complete response in 7 of 8 patients with CGD with invasive mold infections (7 proven cases and 1 possible case) after failure or intolerance of treatment with standard antifungal agents. In this preliminary study, salvage treatment with posaconazole was safe and effective.Entities:
Mesh:
Substances:
Year: 2005 PMID: 15889369 DOI: 10.1086/430068
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079