Literature DB >> 15889161

Inhibition studies on salicylate synthase.

Richard J Payne1, Olivier Kerbarh, Ricardo Nunez Miguel, Andrew D Abell, Chris Abell.   

Abstract

Analogues of chorismate and isochorismate were designed and tested as potential inhibitors in the first inhibition study against a salicylate synthase.

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Year:  2005        PMID： 15889161     DOI： 10.1039/b503800f

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  10 in total

1.  Antitubercular nucleosides that inhibit siderophore biosynthesis: SAR of the glycosyl domain.

Authors:  Ravindranadh V Somu; Daniel J Wilson; Eric M Bennett; Helena I Boshoff; Laura Celia; Brian J Beck; Clifton E Barry; Courtney C Aldrich
Journal:  J Med Chem       Date:  2006-12-28       Impact factor: 7.446

Review 2.  Small molecule inhibition of microbial natural product biosynthesis-an emerging antibiotic strategy.

Authors:  Justin S Cisar; Derek S Tan
Journal:  Chem Soc Rev       Date:  2008-05-21       Impact factor: 54.564

Review 3.  Siderophore-based iron acquisition and pathogen control.

Authors:  Marcus Miethke; Mohamed A Marahiel
Journal:  Microbiol Mol Biol Rev       Date:  2007-09       Impact factor: 11.056

4.  Stereocontrolled Synthesis of a Potential Transition-State Inhibitor of the Salicylate Synthase MbtI from Mycobacterium tuberculosis.

Authors:  Zheng Liu; Feng Liu; Courtney C Aldrich
Journal:  J Org Chem       Date:  2015-06-16       Impact factor: 4.354

Review 5.  Breaking a pathogen's iron will: Inhibiting siderophore production as an antimicrobial strategy.

Authors:  Audrey L Lamb
Journal:  Biochim Biophys Acta       Date:  2015-05-10

6.  Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism.

Authors:  Kathleen M Meneely; Qianyi Luo; Andrew P Riley; Byron Taylor; Anuradha Roy; Ross L Stein; Thomas E Prisinzano; Audrey L Lamb
Journal:  Bioorg Med Chem       Date:  2014-09-16       Impact factor: 3.641

7.  Inhibitors of the salicylate synthase (MbtI) from Mycobacterium tuberculosis discovered by high-throughput screening.

Authors:  Mahalakshmi Vasan; João Neres; Jessica Williams; Daniel J Wilson; Aaron M Teitelbaum; Rory P Remmel; Courtney C Aldrich
Journal:  ChemMedChem       Date:  2010-12-03       Impact factor: 3.466

8.  Synthesis of Transition-State Inhibitors of Chorismate Utilizing Enzymes from Bromobenzene cis-1,2-Dihydrodiol.

Authors:  Xiao-Kang Zhang; Feng Liu; William D Fiers; Wen-Mei Sun; Jun Guo; Zheng Liu; Courtney C Aldrich
Journal:  J Org Chem       Date:  2017-03-17       Impact factor: 4.354

9.  The structure of MbtI from Mycobacterium tuberculosis, the first enzyme in the biosynthesis of the siderophore mycobactin, reveals it to be a salicylate synthase.

Authors:  Anthony J Harrison; Minmin Yu; Therés Gårdenborg; Martin Middleditch; Rochelle J Ramsay; Edward N Baker; J Shaun Lott
Journal:  J Bacteriol       Date:  2006-09       Impact factor: 3.490

10.  An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.

Authors:  Kathleen M Meneely; Jesse A Sundlov; Andrew M Gulick; Graham R Moran; Audrey L Lamb
Journal:  J Am Chem Soc       Date:  2016-07-19       Impact factor: 15.419
  10 in total

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