| Literature DB >> 15883816 |
Abstract
A minireview is presented concerning the use of mercapturic acids as biological exposure index for electrophilic chemicals. Besides pure analytical aspects, this minireview considers possible issues in relation to (a) the added value of mercapturic acids as compared to other well validated biomarkers of exposure and (b) the high inter-individual variability in mercapturic acids excretion. Recent field and/or experimental studies confirm the usefulness of mercapturic acids as biological exposure index for electrophilic chemicals and suggest the interest of a toxicogenetic approach for a better interpretation of the results of biological monitoring.Entities:
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Year: 2005 PMID: 15883816 DOI: 10.1007/s00420-005-0620-z
Source DB: PubMed Journal: Int Arch Occup Environ Health ISSN: 0340-0131 Impact factor: 3.015