Literature DB >> 15883385

The use of oscillatory signals in the study of genetic networks.

Ovidiu Lipan1, Wing H Wong.   

Abstract

The structure of a genetic network is uncovered by studying its response to external stimuli (input signals). We present a theory of propagation of an input signal through a linear stochastic genetic network. We found that there are important advantages in using oscillatory signals over step or impulse signals and that the system may enter into a pure fluctuation resonance for a specific input frequency.

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Year:  2005        PMID: 15883385      PMCID: PMC1129090          DOI: 10.1073/pnas.0403790102

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  21 in total

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2.  Extensive and divergent circadian gene expression in liver and heart.

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5.  Prediction and measurement of an autoregulatory genetic module.

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7.  Intrinsic and extrinsic contributions to stochasticity in gene expression.

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  25 in total

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3.  The frequency dependence of osmo-adaptation in Saccharomyces cerevisiae.

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10.  Metabolic gene regulation in a dynamically changing environment.

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