Literature DB >> 15871231

Perchlorate and iodide in dairy and breast milk.

Andrea B Kirk1, P Kalyani Martinelango, Kang Tian, Aniruddha Dutta, Ernest E Smith, Purnendu K Dasgupta.   

Abstract

Perchlorate inhibits iodide uptake and may impair thyroid and neurodevelopment in infants. Recently, we unambiguously identified the presence of perchlorate in all seven brands of dairy milk randomly purchased from grocery stores in Lubbock, TX. How widespread is perchlorate in milk? Perchlorate in 47 dairy milk samples from 11 states and in 36 human milk samples from 18 states were measured. Iodide was also measured in a number of the samples. Perchlorate was detectable in 81 of 82 samples. The dairy and breast milk means were, respectively, 2.0 and 10.5 microg/L with the corresponding maximum values of 11 and 92 microg/L. Perchlorate is present in virtually all milk samples, the average concentration in breast milk is five times higher than in dairy milk. Although the number of available measurements are few at this point, for breast milk samples with a perchlorate content greater than 10 microg/L, the iodide content is linearly correlated with the inverse of the perchlorate concentration with a r2 of >0.9 (n = 6). The presence of perchlorate in the milk lowers the iodide content and may impair thyroid development in infants. On the basis of limited available data, iodide levels in breast milk may be significantly lower than it was two decades ago. Recommended iodine intake by pregnant and lactating women may need to be revised upward.

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Year:  2005        PMID: 15871231     DOI: 10.1021/es048118t

Source DB:  PubMed          Journal:  Environ Sci Technol        ISSN: 0013-936X            Impact factor:   9.028


  53 in total

1.  Temporal variability in urinary concentrations of perchlorate, nitrate, thiocyanate and iodide among children.

Authors:  Nancy Mervish; Ben Blount; Liza Valentin-Blasini; Barbara Brenner; Maida P Galvez; Mary S Wolff; Susan L Teitelbaum
Journal:  J Expo Sci Environ Epidemiol       Date:  2011-12-14       Impact factor: 5.563

Review 2.  Environmental exposures and autoimmune thyroid disease.

Authors:  Gregory A Brent
Journal:  Thyroid       Date:  2010-07       Impact factor: 6.568

Review 3.  Perchlorate, iodine and the thyroid.

Authors:  Angela M Leung; Elizabeth N Pearce; Lewis E Braverman
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2010-02       Impact factor: 4.690

4.  Identification of a perchlorate reduction genomic island with novel regulatory and metabolic genes.

Authors:  Ryan A Melnyk; Anna Engelbrektson; Iain C Clark; Hans K Carlson; Kathy Byrne-Bailey; John D Coates
Journal:  Appl Environ Microbiol       Date:  2011-08-19       Impact factor: 4.792

5.  Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum.

Authors:  Alex Stagnaro-Green; Marcos Abalovich; Erik Alexander; Fereidoun Azizi; Jorge Mestman; Roberto Negro; Angelita Nixon; Elizabeth N Pearce; Offie P Soldin; Scott Sullivan; Wilmar Wiersinga
Journal:  Thyroid       Date:  2011-07-25       Impact factor: 6.568

6.  (Per)chlorate reduction by an acetogenic bacterium, Sporomusa sp., isolated from an underground gas storage.

Authors:  Melike Balk; Farrakh Mehboob; Antonie H van Gelder; W Irene C Rijpstra; Jaap S Sinninghe Damsté; Alfons J M Stams
Journal:  Appl Microbiol Biotechnol       Date:  2010-08-03       Impact factor: 4.813

7.  Goiter and multiple food allergies.

Authors:  Stefanie Leniszewski; Richard Mauseth
Journal:  Int J Pediatr Endocrinol       Date:  2009-04-08

Review 8.  Basis of the Massachusetts reference dose and drinking water standard for perchlorate.

Authors:  Tsedash Zewdie; C Mark Smith; Michael Hutcheson; Carol Rowan West
Journal:  Environ Health Perspect       Date:  2010-01       Impact factor: 9.031

9.  Description of the novel perchlorate-reducing bacteria Dechlorobacter hydrogenophilus gen. nov., sp. nov.and Propionivibrio militaris, sp. nov.

Authors:  J Cameron Thrash; Jarrod Pollock; Tamas Torok; John D Coates
Journal:  Appl Microbiol Biotechnol       Date:  2010-03       Impact factor: 4.813

Review 10.  Perchlorate: health effects and technologies for its removal from water resources.

Authors:  Asha Srinivasan; Thiruvenkatachari Viraraghavan
Journal:  Int J Environ Res Public Health       Date:  2009-04-14       Impact factor: 3.390

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