Literature DB >> 15868978

Thyroid disease in a rural Kenyan hospital.

A G Hill1, I Mwangi, L Wagana.   

Abstract

OBJECTIVES: To review the spectrum of thyroid pathology diagnoses likely to be encountered by surgeons working in East African hospitals.
DESIGN: A retrospective review of all thyroidectomies performed over a three year period.
SETTING: A rural church based hospital in Kenya.
SUBJECTS: Two hundred and twenty two patients who underwent thyroidectomy over a three year period at Kijabe hospital.
INTERVENTIONS: A simple protocol was used to manage thyroid disease involving history, clinical examination, measurement of TSH and needle aspiration of lesions where appropriate, and excision when clinically indicated. MAIN OUTCOME MEASURES: Clinical diagnosis, tribe, operation performed, pathology, and complications of surgery.
RESULTS: Two hundred and twenty thyroidectomies were performed. Overall there was a malignancy rate of 11.7% (15 papillary, 11 follicular). The commonest pathological diagnosis was multinodular goitre (47%). Graves' disease was a relatively common diagnosis in this series (13%). The mortality rate was 0.5% and the morbidity rate was 3.6%.
CONCLUSION: Graves' disease is not as uncommon in rural Africa as previously thought. Malignancy is relatively common and there appears to be a change in the papillary to follicular cancer ratio perhaps reflecting widespread iodinisation of salt in Kenya.

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Year:  2004        PMID: 15868978     DOI: 10.4314/eamj.v81i12.9248

Source DB:  PubMed          Journal:  East Afr Med J        ISSN: 0012-835X


  3 in total

1.  Patterns of Thyroid Cancers in Southeastern Nigeria: A 15 Year Histopathologic Review (2000-2014).

Authors:  Francis Ikechukwu Ukekwe; Daniel Bankole Olusina; Philip C N Okere
Journal:  J Clin Diagn Res       Date:  2017-08-01

2.  Epidemiology of thyroid diseases in Africa.

Authors:  Anthonia Okeoghene Ogbera; Sonny Folunrusho Kuku
Journal:  Indian J Endocrinol Metab       Date:  2011-07

3.  Iodine deficiency among goiter patients in rural South Sudan.

Authors:  Chep C Chuot; Moses Galukande; Charles Ibingira; Nicholas Kisa; Jane Odubu Fualal
Journal:  BMC Res Notes       Date:  2014-10-23
  3 in total

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