Literature DB >> 15868397

Introduction to poly(ADP-ribose) metabolism.

J Diefenbach1, A Bürkle.   

Abstract

Poly(ADP-ribosyl)ation is a posttranslational modification of proteins in eukaryotic cells catalysed by a family of NAD+ ADP-ribosyl transferases, the poly(ADP-ribose) polymerases (PARPs). PARP-encoding genes now constitute a superfamily of at least 18 members encoding proteins that share homology with the catalytic domain of the founding member, PARP-1. Poly(ADP-ribose) metabolism is of central importance in a wide variety of biological processes including maintenance of genomic stability, DNA repair, transcriptional regulation, centromere function, modulation of telomere length, regulation of proteasomal protein degradation, regulation of endosomal vesicle trafficking and apoptosis. The life cycle of poly(ADP-ribose) is discussed in the following section. In addition, an overview of the genes and proteins involved in poly(ADP-ribose) metabolism and their possible cellular function is provided.

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Year:  2005        PMID: 15868397     DOI: 10.1007/s00018-004-4503-3

Source DB:  PubMed          Journal:  Cell Mol Life Sci        ISSN: 1420-682X            Impact factor:   9.261


  4 in total

1.  2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the Heart Rhythm Society.

Authors:  Craig T January; L Samuel Wann; Joseph S Alpert; Hugh Calkins; Joaquin E Cigarroa; Joseph C Cleveland; Jamie B Conti; Patrick T Ellinor; Michael D Ezekowitz; Michael E Field; Katherine T Murray; Ralph L Sacco; William G Stevenson; Patrick J Tchou; Cynthia M Tracy; Clyde W Yancy
Journal:  Circulation       Date:  2014-03-28       Impact factor: 29.690

2.  2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS.

Authors:  Paulus Kirchhof; Stefano Benussi; Dipak Kotecha; Anders Ahlsson; Dan Atar; Barbara Casadei; Manuel Castella; Hans-Christoph Diener; Hein Heidbuchel; Jeroen Hendriks; Gerhard Hindricks; Antonis S Manolis; Jonas Oldgren; Bogdan Alexandru Popescu; Ulrich Schotten; Bart Van Putte; Panagiotis Vardas
Journal:  Eur Heart J       Date:  2016-08-27       Impact factor: 29.983

3.  Edoxaban versus enoxaparin-warfarin in patients undergoing cardioversion of atrial fibrillation (ENSURE-AF): a randomised, open-label, phase 3b trial.

Authors:  Andreas Goette; Jose L Merino; Michael D Ezekowitz; Dmitry Zamoryakhin; Michael Melino; James Jin; Michele F Mercuri; Michael A Grosso; Victor Fernandez; Naab Al-Saady; Natalya Pelekh; Bela Merkely; Sergey Zenin; Mykola Kushnir; Jindrich Spinar; Valeriy Batushkin; Joris R de Groot; Gregory Y H Lip
Journal:  Lancet       Date:  2016-08-30       Impact factor: 79.321

4.  2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: The Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC). Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC).

Authors:  Silvia G Priori; Carina Blomström-Lundqvist; Andrea Mazzanti; Nico Blom; Martin Borggrefe; John Camm; Perry Mark Elliott; Donna Fitzsimons; Robert Hatala; Gerhard Hindricks; Paulus Kirchhof; Keld Kjeldsen; Karl-Heinz Kuck; Antonio Hernandez-Madrid; Nikolaos Nikolaou; Tone M Norekvål; Christian Spaulding; Dirk J Van Veldhuisen
Journal:  Eur Heart J       Date:  2015-08-29       Impact factor: 29.983

  4 in total
  31 in total

1.  Induction of mitochondrial dysfunction by poly(ADP-ribose) polymer: implication for neuronal cell death.

Authors:  Seung-Hoon Baek; Ok-Nam Bae; Eun-Kyoung Kim; Seong-Woon Yu
Journal:  Mol Cells       Date:  2013-08-29       Impact factor: 5.034

2.  Hydrolysis of O-acetyl-ADP-ribose isomers by ADP-ribosylhydrolase 3.

Authors:  Atsushi Kasamatsu; Motoyuki Nakao; Brian C Smith; Lindsay R Comstock; Tohru Ono; Jiro Kato; John M Denu; Joel Moss
Journal:  J Biol Chem       Date:  2011-04-17       Impact factor: 5.157

3.  The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes.

Authors:  Ben Buelow; Yumei Song; Andrew M Scharenberg
Journal:  J Biol Chem       Date:  2008-07-03       Impact factor: 5.157

4.  Mechanism of ADP-ribosylation removal revealed by the structure and ligand complexes of the dimanganese mono-ADP-ribosylhydrolase DraG.

Authors:  Catrine L Berthold; He Wang; Stefan Nordlund; Martin Högbom
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-12       Impact factor: 11.205

5.  NSAIDs may regulate EGR-1-mediated induction of reactive oxygen species and non-steroidal anti-inflammatory drug-induced gene (NAG)-1 to initiate intrinsic pathway of apoptosis for the chemoprevention of colorectal cancer.

Authors:  Vivek Vaish; Honit Piplani; Chandan Rana; Kim Vaiphei; Sankar Nath Sanyal
Journal:  Mol Cell Biochem       Date:  2013-02-23       Impact factor: 3.396

6.  PARP1 suppresses homologous recombination events in mice in vivo.

Authors:  Alison Claybon; Bijal Karia; Crystal Bruce; Alexander J R Bishop
Journal:  Nucleic Acids Res       Date:  2010-07-21       Impact factor: 16.971

Review 7.  Activation of PARP by oxidative stress induced by β-amyloid: implications for Alzheimer's disease.

Authors:  Rosella Abeti; Michael R Duchen
Journal:  Neurochem Res       Date:  2012-10-18       Impact factor: 3.996

8.  Large-scale preparation and characterization of poly(ADP-ribose) and defined length polymers.

Authors:  Edwin S Tan; Kristin A Krukenberg; Timothy J Mitchison
Journal:  Anal Biochem       Date:  2012-06-26       Impact factor: 3.365

9.  Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells.

Authors:  Katalin Erdélyi; Péter Bai; István Kovács; Eva Szabó; Gábor Mocsár; Annamária Kakuk; Csaba Szabó; Pál Gergely; László Virág
Journal:  FASEB J       Date:  2009-07-01       Impact factor: 5.191

Review 10.  Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes.

Authors:  Ashok Agarwal; Reda Z Mahfouz; Rakesh K Sharma; Oli Sarkar; Devna Mangrola; Premendu P Mathur
Journal:  Reprod Biol Endocrinol       Date:  2009-12-05       Impact factor: 5.211

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