Literature DB >> 15866029

RNA silencing and genome regulation.

Ricardo Almeida1, Robin C Allshire.   

Abstract

Closely related RNA silencing phenomena such as posttranscriptional and transcriptional gene silencing (PTGS and TGS), quelling and RNA interference (RNAi) represent different forms of a conserved ancestral process. The biological relevance of these RNA-directed mechanisms of silencing in gene regulation, genome defence and chromosomal structure is rapidly being unravelled. Here, we review the recent developments in the field of RNA silencing in relation to other epigenetic phenomena and discuss the significance of this process and its targets in the regulation of modern eukaryotic genomes.

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Year:  2005        PMID： 15866029     DOI： 10.1016/j.tcb.2005.03.006

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  72 in total

Review 1.  Recent progress in the understanding of tissue culture-induced genome level changes in plants and potential applications.

Authors:  Anjanasree K Neelakandan; Kan Wang
Journal:  Plant Cell Rep       Date:  2011-12-17       Impact factor: 4.570

2.  The Functions of RNA-Dependent RNA Polymerases in Arabidopsis.

Authors:  Matthew R Willmann; Matthew W Endres; Rebecca T Cook; Brian D Gregory
Journal:  Arabidopsis Book       Date:  2011-07-31

3.  Device-based local delivery of siRNA against mammalian target of rapamycin (mTOR) in a murine subcutaneous implant model to inhibit fibrous encapsulation.

Authors:  Hironobu Takahashi; Yuwei Wang; David W Grainger
Journal:  J Control Release       Date:  2010-08-19       Impact factor: 9.776

4.  siRNA knock-down of RANK signaling to control osteoclast-mediated bone resorption.

Authors:  Yuwei Wang; David W Grainger
Journal:  Pharm Res       Date:  2010-03-24       Impact factor: 4.200

Review 5.  Structural domains in RNAi.

Authors:  Robert E Collins; Xiaodong Cheng
Journal:  FEBS Lett       Date:  2005-08-09       Impact factor: 4.124

6.  Accumulation of small murine minor satellite transcripts leads to impaired centromeric architecture and function.

Authors:  Haniaa Bouzinba-Segard; Adeline Guais; Claire Francastel
Journal:  Proc Natl Acad Sci U S A       Date:  2006-05-26       Impact factor: 11.205

Review 7.  RNAi therapeutics: principles, prospects and challenges.

Authors:  Lars Aagaard; John J Rossi
Journal:  Adv Drug Deliv Rev       Date:  2007-03-16       Impact factor: 15.470

8.  Tandem 41-bp repeats in chicken and Japanese quail genomes: FISH mapping and transcription analysis on lampbrush chromosomes.

Authors:  Svetlana Deryusheva; Alla Krasikova; Tatiana Kulikova; Elena Gaginskaya
Journal:  Chromosoma       Date:  2007-07-10       Impact factor: 4.316

9.  Epigenetic silencing of transposable elements: a trade-off between reduced transposition and deleterious effects on neighboring gene expression.

Authors:  Jesse D Hollister; Brandon S Gaut
Journal:  Genome Res       Date:  2009-05-28       Impact factor: 9.043

Review 10.  RNAi mechanisms and applications.

Authors:  Daniel Kim; John Rossi
Journal:  Biotechniques       Date:  2008-04       Impact factor: 1.993
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