Literature DB >> 15863346

Blood flow and structure interactions in a stented abdominal aortic aneurysm model.

Zhonghua Li1, Clement Kleinstreuer.   

Abstract

Since the introduction of endovascular techniques in the early 1990s for the treatment of abdominal aortic aneurysms (AAAs), the insertion of an endovascular graft (EVG) into the affected artery segment has been greatly successful for a certain group of AAA patients and is continuously evolving. However, although minimally invasive endovascular aneurysm repair (EVAR) is very attractive, post-operative complications may occur. Typically, they are the result of excessive fluid-structure interaction dynamics, possibly leading to EVG migration. Considering a 3D stented AAA, a coupled fluid flow and solid mechanics solver was employed to simulate and analyze the interactive dynamics, i.e., pulsatile blood flow in the EVG lumen, pressure levels in the stagnant blood filling the AAA cavity, as well as stresses and displacements in the EVG and AAA walls. The validated numerical results show that a securely placed EVG shields the diseased AAA wall from the pulsatile blood pressure and hence keeps the maximum wall stress 20 times below the wall stress value in the non-stented AAA. The sac pressure is reduced significantly but remains non-zero and transient, caused by the complex fluid-structure interactions between luminal blood flow, EVG wall, stagnant sac blood, and aneurysm wall. The time-varying drag force on the EVG exerted by physiological blood flow is unavoidable, where for patients with severe hypertension the risk of EVG migration is very high.

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Year:  2005        PMID: 15863346     DOI: 10.1016/j.medengphy.2004.12.003

Source DB:  PubMed          Journal:  Med Eng Phys        ISSN: 1350-4533            Impact factor:   2.242


  27 in total

Review 1.  Patient-specific modeling of cardiovascular mechanics.

Authors:  C A Taylor; C A Figueroa
Journal:  Annu Rev Biomed Eng       Date:  2009       Impact factor: 9.590

2.  Modelling the human pharyngeal airway: validation of numerical simulations using in vitro experiments.

Authors:  Franz Chouly; Annemie Van Hirtum; Pierre-Yves Lagrée; Xavier Pelorson; Yohan Payan
Journal:  Med Biol Eng Comput       Date:  2008-11-08       Impact factor: 2.602

3.  A computational framework for investigating the positional stability of aortic endografts.

Authors:  Anamika Prasad; Nan Xiao; Xiao-Yan Gong; Christopher K Zarins; C Alberto Figueroa
Journal:  Biomech Model Mechanobiol       Date:  2012-11-10

4.  Investigation of material modeling in fluid-structure interaction analysis of an idealized three-layered abdominal aorta: aneurysm initiation and fully developed aneurysms.

Authors:  Fatma Gulden Simsek; Young W Kwon
Journal:  J Biol Phys       Date:  2015-01-27       Impact factor: 1.365

5.  Are Non-Newtonian Effects Important in Hemodynamic Simulations of Patients With Autogenous Fistula?

Authors:  S M Javid Mahmoudzadeh Akherat; Kevin Cassel; Michael Boghosian; Promila Dhar; Mary Hammes
Journal:  J Biomech Eng       Date:  2017-04-01       Impact factor: 2.097

6.  In vitro validation of finite-element model of AAA hemodynamics incorporating realistic outlet boundary conditions.

Authors:  Ethan O Kung; Andrea S Les; Francisco Medina; Ryan B Wicker; Michael V McConnell; Charles A Taylor
Journal:  J Biomech Eng       Date:  2011-04       Impact factor: 2.097

7.  In vitro validation of finite element analysis of blood flow in deformable models.

Authors:  Ethan O Kung; Andrea S Les; C Alberto Figueroa; Francisco Medina; Karina Arcaute; Ryan B Wicker; Michael V McConnell; Charles A Taylor
Journal:  Ann Biomed Eng       Date:  2011-03-15       Impact factor: 3.934

Review 8.  [Simulation of blood flow within the abdominal aorta. Computational fluid dynamics in abdominal aortic aneurysms before and after interventions].

Authors:  T Frauenfelder; E Boutsianis; H Alkadhi; B Marincek; T Schertler
Journal:  Radiologe       Date:  2007-11       Impact factor: 0.635

Review 9.  Biomechanical issues in endovascular device design.

Authors:  James E Moore
Journal:  J Endovasc Ther       Date:  2009-02       Impact factor: 3.487

10.  Finite-element-based matching of pre- and intraoperative data for image-guided endovascular aneurysm repair.

Authors:  Aurélien Duménil; Adrien Kaladji; Miguel Castro; Simon Esneault; Antoine Lucas; Michel Rochette; Cemil Göksu; Pascal Haigron
Journal:  IEEE Trans Biomed Eng       Date:  2012-12-20       Impact factor: 4.538

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