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Literature DB >> 15861447

Evidence that electrostatic interactions dictate the ligand-induced arrest of RNA global flexibility.

Stephen W Pitt¹, Qi Zhang, Dinshaw J Patel, Hashim M Al-Hashimi.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2005 PMID： 15861447 PMCID： PMC4690522 DOI： 10.1002/anie.200500075

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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34 in total

1. Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome.

Authors: T Pape; W Wintermeyer; M V Rodnina
Journal: Nat Struct Biol Date: 2000-02

2. Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA.

Authors: Kenneth E Lind; Zhihua Du; Koh Fujinaga; B Matija Peterlin; Thomas L James
Journal: Chem Biol Date: 2002-02

Review 3. Targeting the HIV trans-activation responsive region--approaches towards RNA-binding drugs.

Authors: Andreas Krebs; Verena Ludwig; Oliver Boden; Michael W Göbel
Journal: Chembiochem Date: 2003-10-06 Impact factor: 3.164

4. Rational design of inhibitors of HIV-1 TAR RNA through the stabilisation of electrostatic "hot spots".

Authors: Ben Davis; Mohammad Afshar; Gabriele Varani; Alastair I H Murchie; Jonathan Karn; Georg Lentzen; Martin Drysdale; Justin Bower; Andrew J Potter; Ian D Starkey; Terry Swarbrick; Fareed Aboul-ela
Journal: J Mol Biol Date: 2004-02-13 Impact factor: 5.469

Review 5. Deciphering RNA recognition: aminoglycoside binding to the hammerhead ribozyme.

Authors: Y Tor; T Hermann; E Westhof
Journal: Chem Biol Date: 1998-11

6. Structural rearrangements of HIV-1 Tat-responsive RNA upon binding of neomycin B.

Authors: C Faber; H Sticht; K Schweimer; P Rösch
Journal: J Biol Chem Date: 2000-07-07 Impact factor: 5.157

7. Docking of cationic antibiotics to negatively charged pockets in RNA folds.

Authors: T Hermann; E Westhof
Journal: J Med Chem Date: 1999-04-08 Impact factor: 7.446

8. The antibiotic thiostrepton inhibits a functional transition within protein L11 at the ribosomal GTPase centre.

Authors: B T Porse; I Leviev; A S Mankin; R A Garrett
Journal: J Mol Biol Date: 1998-02-20 Impact factor: 5.469

9. Concerted motions in HIV-1 TAR RNA may allow access to bound state conformations: RNA dynamics from NMR residual dipolar couplings.

Authors: Hashim M Al-Hashimi; Yuying Gosser; Andrey Gorin; Weidong Hu; Ananya Majumdar; Dinshaw J Patel
Journal: J Mol Biol Date: 2002-01-11 Impact factor: 5.469

10. Structure of HIV-1 TAR RNA in the absence of ligands reveals a novel conformation of the trinucleotide bulge.

Authors: F Aboul-ela; J Karn; G Varani
Journal: Nucleic Acids Res Date: 1996-10-15 Impact factor: 16.971

16 in total

1. Structural plasticity and Mg2+ binding properties of RNase P P4 from combined analysis of NMR residual dipolar couplings and motionally decoupled spin relaxation.

Authors: Melissa M Getz; Andy J Andrews; Carol A Fierke; Hashim M Al-Hashimi
Journal: RNA Date: 2006-12-28 Impact factor: 4.942

2. Impact of static and dynamic A-form heterogeneity on the determination of RNA global structural dynamics using NMR residual dipolar couplings.

Authors: Catherine Musselman; Stephen W Pitt; Kush Gulati; Lesley L Foster; Ioan Andricioaei; Hashim M Al-Hashimi
Journal: J Biomol NMR Date: 2006-11-01 Impact factor: 2.835

3. Probing Na(+)-induced changes in the HIV-1 TAR conformational dynamics using NMR residual dipolar couplings: new insights into the role of counterions and electrostatic interactions in adaptive recognition.

Authors: Anette Casiano-Negroni; Xiaoyan Sun; Hashim M Al-Hashimi
Journal: Biochemistry Date: 2007-05-09 Impact factor: 3.162

4. Characterizing complex dynamics in the transactivation response element apical loop and motional correlations with the bulge by NMR, molecular dynamics, and mutagenesis.

Authors: Elizabeth A Dethoff; Alexandar L Hansen; Catherine Musselman; Eric D Watt; Ioan Andricioaei; Hashim M Al-Hashimi
Journal: Biophys J Date: 2008-07-11 Impact factor: 4.033

5. Dynamic motions of the HIV-1 frameshift site RNA.

Authors: Kathryn D Mouzakis; Elizabeth A Dethoff; Marco Tonelli; Hashim Al-Hashimi; Samuel E Butcher
Journal: Biophys J Date: 2015-02-03 Impact factor: 4.033

6. Characterizing the relative orientation and dynamics of RNA A-form helices using NMR residual dipolar couplings.

Authors: Maximillian H Bailor; Catherine Musselman; Alexandar L Hansen; Kush Gulati; Dinshaw J Patel; Hashim M Al-Hashimi
Journal: Nat Protoc Date: 2007 Impact factor: 13.491

7. The internal dynamics of mini c TAR DNA probed by electron paramagnetic resonance of nitroxide spin-labels at the lower stem, the loop, and the bulge.

Authors: Yan Sun; Ziwei Zhang; Vladimir M Grigoryants; William K Myers; Fei Liu; Keith A Earle; Jack H Freed; Charles P Scholes
Journal: Biochemistry Date: 2012-10-18 Impact factor: 3.162

8. Variable helix elongation as a tool to modulate RNA alignment and motional couplings.

Authors: Elizabeth A Dethoff; Alexandar L Hansen; Qi Zhang; Hashim M Al-Hashimi
Journal: J Magn Reson Date: 2009-09-30 Impact factor: 2.229

9. Resolving fast and slow motions in the internal loop containing stem-loop 1 of HIV-1 that are modulated by Mg2+ binding: role in the kissing-duplex structural transition.

Authors: Xiaoyan Sun; Qi Zhang; Hashim M Al-Hashimi
Journal: Nucleic Acids Res Date: 2007-02-20 Impact factor: 16.971

10. Constructing RNA dynamical ensembles by combining MD and motionally decoupled NMR RDCs: new insights into RNA dynamics and adaptive ligand recognition.

Authors: Aaron T Frank; Andrew C Stelzer; Hashim M Al-Hashimi; Ioan Andricioaei
Journal: Nucleic Acids Res Date: 2009-04-15 Impact factor: 16.971