Literature DB >> 15858043

Residues in the murine leukemia virus capsid that differentially govern resistance to mouse Fv1 and human Ref1 restrictions.

Adeline Lassaux1, Marc Sitbon, Jean-Luc Battini.   

Abstract

We identified new residues within a 101-amino-acid stretch of the murine leukemia virus capsid that differentially modulate resistance and susceptibility to the mouse Fv1 and human Ref1 genes. Among these residues, aspartate 92 and histidine 117 are both required for Fv1(b) resistance, whereas the latter is sufficient to confer Ref1 resistance.

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Year:  2005        PMID: 15858043      PMCID: PMC1091700          DOI: 10.1128/JVI.79.10.6560-6564.2005

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  34 in total

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  21 in total

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