Literature DB >> 15855535

Pharmacokinetics of tenofovir in breast milk of lactating rhesus macaques.

Koen K A Van Rompay1, Marta Hamilton, Brian Kearney, Norbert Bischofberger.   

Abstract

To study tenofovir transfer into milk, two lactating macaques were given a subcutaneous dose of tenofovir (30 mg/kg of body weight). Peak concentrations and area under the curve values of tenofovir in milk were approximately 3 and approximately 20% of those detected in serum, respectively.

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Year:  2005        PMID： 15855535      PMCID： PMC1087653          DOI： 10.1128/AAC.49.5.2093-2094.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


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8.  Biological effects of short-term or prolonged administration of 9-[2-(phosphonomethoxy)propyl]adenine (tenofovir) to newborn and infant rhesus macaques.

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