Literature DB >> 15853306

Reversible insulin self-assembly under carbohydrate control.

Thomas Hoeg-Jensen1, Svend Havelund, Peter K Nielsen, Jan Markussen.   

Abstract

Insulin with built-in pairs of boronates and polyols can produce soluble high molecular weight self-assemblies under control by carbohydrates. The illustrated principle has potential utility for general protein and peptide protraction and controlled drug release.

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Year:  2005        PMID: 15853306     DOI: 10.1021/ja051038k

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  15 in total

1.  Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.

Authors:  Piotr Borowicz; Elżbieta Bednarek; Wojciech Bocian; Jerzy Sitkowski; Beata Jaworska; Jerzy Mikołajczyk; Tadeusz Głąbski; Dorota Stadnik; Weronika Surmacz; Monika Bogiel; Lech Kozerski
Journal:  J Biomol NMR       Date:  2012-02-14       Impact factor: 2.835

Review 2.  Glucose-Responsive Insulin and Delivery Systems: Innovation and Translation.

Authors:  Jinqiang Wang; Zejun Wang; Jicheng Yu; Anna R Kahkoska; John B Buse; Zhen Gu
Journal:  Adv Mater       Date:  2019-08-18       Impact factor: 30.849

Review 3.  Pursuit of a perfect insulin.

Authors:  Alexander N Zaykov; John P Mayer; Richard D DiMarchi
Journal:  Nat Rev Drug Discov       Date:  2016-03-18       Impact factor: 84.694

4.  Simple Protein Modification Using Zwitterionic Polymer to Mitigate the Bioactivity Loss of Conjugated Insulin.

Authors:  Jinbing Xie; Yang Lu; Wei Wang; Hui Zhu; Zhigang Wang; Zhiqiang Cao
Journal:  Adv Healthc Mater       Date:  2017-03-24       Impact factor: 9.933

5.  Glucose-responsive insulin by molecular and physical design.

Authors:  Naveed A Bakh; Abel B Cortinas; Michael A Weiss; Robert S Langer; Daniel G Anderson; Zhen Gu; Sanjoy Dutta; Michael S Strano
Journal:  Nat Chem       Date:  2017-09-22       Impact factor: 24.427

Review 6.  Glucose-Responsive Insulin Through Bioconjugation Approaches.

Authors:  Maria M Disotuar; Diao Chen; Nai-Pin Lin; Danny Hung-Chieh Chou
Journal:  J Diabetes Sci Technol       Date:  2019-06-19

7.  Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates.

Authors:  Danny Hung-Chieh Chou; Matthew J Webber; Benjamin C Tang; Amy B Lin; Lavanya S Thapa; David Deng; Jonathan V Truong; Abel B Cortinas; Robert Langer; Daniel G Anderson
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-09       Impact factor: 11.205

8.  Engineering Synthetically Modified Insulin for Glucose-Responsive Diabetes Therapy.

Authors:  Matthew J Webber; Daniel G Anderson; Robert Langer
Journal:  Expert Rev Endocrinol Metab       Date:  2015-07-18

Review 9.  Smart approaches to glucose-responsive drug delivery.

Authors:  Matthew J Webber; Daniel G Anderson
Journal:  J Drug Target       Date:  2015       Impact factor: 5.121

Review 10.  Developing Insulin Delivery Devices with Glucose Responsiveness.

Authors:  Zejun Wang; Jinqiang Wang; Anna R Kahkoska; John B Buse; Zhen Gu
Journal:  Trends Pharmacol Sci       Date:  2020-11-26       Impact factor: 14.819

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