Literature DB >> 15853301

Enzymatic approach to unnatural glycosides with diverse aglycon scaffolds using glycosyltransferase VinC.

Atsushi Minami1, Rei Uchida, Tadashi Eguchi, Katsumi Kakinuma.   

Abstract

Glycosyltransferase VinC was explored for a construction of glycoside libraries using dTDP-vicenisamine and structurally unrelated unnatural aglycons, and new unnatural vicenisaminides were successfully constructed. Structural elements of aglycon recognition by VinC were proposed by modeling studies and were confirmed by the success of transglycosylation upon a designed aglycon.

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Year:  2005        PMID： 15853301     DOI： 10.1021/ja042848j

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  11 in total

1.  Probing the aglycon promiscuity of an engineered glycosyltransferase.

Authors:  Richard W Gantt; Randal D Goff; Gavin J Williams; Jon S Thorson
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

2.  The in vitro characterization of polyene glycosyltransferases AmphDI and NysDI.

Authors:  Changsheng Zhang; Rocco Moretti; Jiqing Jiang; Jon S Thorson
Journal:  Chembiochem       Date:  2008-10-13       Impact factor: 3.164

3.  OleD Loki as a Catalyst for Tertiary Amine and Hydroxamate Glycosylation.

Authors:  Ryan R Hughes; Khaled A Shaaban; Jianjun Zhang; Hongnan Cao; George N Phillips; Jon S Thorson
Journal:  Chembiochem       Date:  2017-01-09       Impact factor: 3.164

4.  Characterization of glycosyltransferase DesVII and its auxiliary partner protein DesVIII in the methymycin/picromycin biosynthetic pathway.

Authors:  Svetlana A Borisova; Hung-Wen Liu
Journal:  Biochemistry       Date:  2010-09-21       Impact factor: 3.162

5.  Modulation of deoxysugar transfer by the elloramycin glycosyltransferase ElmGT through site-directed mutagenesis.

Authors:  Angelina Ramos; Carlos Olano; Alfredo F Braña; Carmen Méndez; José A Salas
Journal:  J Bacteriol       Date:  2009-02-20       Impact factor: 3.490

Review 6.  Natural-product sugar biosynthesis and enzymatic glycodiversification.

Authors:  Christopher J Thibodeaux; Charles E Melançon; Hung-wen Liu
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

Review 7.  The impact of enzyme engineering upon natural product glycodiversification.

Authors:  Gavin J Williams; Richard W Gantt; Jon S Thorson
Journal:  Curr Opin Chem Biol       Date:  2008-10       Impact factor: 8.822

Review 8.  Increasing carbohydrate diversity via amine oxidation: aminosugar, hydroxyaminosugar, nitrososugar, and nitrosugar biosynthesis in bacteria.

Authors:  Shannon C Timmons; Jon S Thorson
Journal:  Curr Opin Chem Biol       Date:  2008-04-18       Impact factor: 8.822

9.  Glycosylation of acyclic and cyclic aglycone substrates by macrolide glycosyltransferase DesVII/DesVIII: analysis and implications.

Authors:  Svetlana A Borisova; Hak Joong Kim; Xiaotao Pu; Hung-Wen Liu
Journal:  Chembiochem       Date:  2008-07-02       Impact factor: 3.164

10.  Crystallization and preliminary X-ray analysis of vicenisaminyltransferase VinC.

Authors:  Eriko Nango; Atsushi Minami; Takashi Kumasaka; Tadashi Eguchi
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2008-05-24
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