Literature DB >> 15849516

Prevalence of blood-borne pathogens in an urban, university-based general surgical practice.

Eric S Weiss1, Martin A Makary, Theresa Wang, Dora Syin, Peter J Pronovost, David Chang, Edward E Cornwell.   

Abstract

OBJECTIVE: To measure the current prevalence of blood-borne pathogens in an urban, university-based, general surgical practice. SUMMARY BACKGROUND DATA: Human immunodeficiency virus (HIV), hepatitis B, and hepatitis C represent significant occupational hazards to the surgeon. While the incidence of these blood-borne pathogens is increasing in the general population, little is known about the current prevalence of these exposures among patients presenting for surgery.
METHODS: We studied 709 consecutive operative cases (July 2003 to June 2004) in a university practice that provides all inpatient, emergency department, and outpatient consultative general surgical services. Trauma cases and bedside procedures were excluded. Data collected included HIV, hepatitis B and C test results, type of operation, age, sex, and history of intravenous drug use.
RESULTS: Testing for blood-borne pathogens was performed in 53% (N = 373) of 709 patients based on abnormal liver function tests, neutropenia, history of IV drug use, or patient request. Thirty-eight percent of all operations (142/373) were found to involve a blood-borne pathogen when tested: HIV (26%), hepatitis B (4%), hepatitis C (35%), and coinfection with HIV and hepatitis C (17%). Forty-seven percent of men tested positive for at least 1 blood-borne pathogen. Seventy-three different types of operations were performed, ranging from Whipple procedures to amputations. Soft-tissue abscess procedures 48% (34/71) and lymph node biopsies 67% (10/15) (P < 0.01) were most often associated with blood-borne pathogens. Infections were more common among men (P < 0.01), patients 41 to 50 years of age (P < 0.01), and patients with a history of intravenous drug use (P < 0.01).
CONCLUSIONS: HIV and hepatitis C infections are common in an urban university general surgical practice, while hepatitis B is less common. In addition, certain operations are associated with significantly increased exposure rates. Given the high incidence of these infections, strategies such as sharpless surgical techniques should be evaluated and implemented to protect surgeons from blood-borne pathogens.

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Year:  2005        PMID: 15849516      PMCID: PMC1357135          DOI: 10.1097/01.sla.0000161174.71460.1f

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  12 in total

Review 1.  Clinical practice. Occupational exposure to HIV in health care settings.

Authors:  Julie Louise Gerberding
Journal:  N Engl J Med       Date:  2003-02-27       Impact factor: 91.245

2.  Preventing sharps injuries in the operating room.

Authors:  Ramon Berguer; Paul J Heller
Journal:  J Am Coll Surg       Date:  2004-09       Impact factor: 6.113

3.  Frequency of puncture injuries in surgeons and estimated risk of HIV infection.

Authors:  A B Lowenfels; G P Wormser; R Jain
Journal:  Arch Surg       Date:  1989-11

4.  Percutaneous injuries during surgical procedures.

Authors:  J I Tokars; D M Bell; D H Culver; R Marcus; M H Mendelson; E P Sloan; B F Farber; D Fligner; M E Chamberland; P S McKibben
Journal:  JAMA       Date:  1992-06-03       Impact factor: 56.272

5.  Needlestick transmission of hepatitis C.

Authors:  Mark S Sulkowski; Stuart C Ray; David L Thomas
Journal:  JAMA       Date:  2002-05-08       Impact factor: 56.272

6.  A survey of occupational blood contact and HIV infection among orthopedic surgeons. The American Academy of Orthopaedic Surgeons Serosurvey Study Committee.

Authors:  J I Tokars; M E Chamberland; C A Schable; D H Culver; M Jones; P S McKibben; D M Bell
Journal:  JAMA       Date:  1992 Jul 22-29       Impact factor: 56.272

7.  Prevalence of infection with human immunodeficiency virus in elective surgery patients.

Authors:  P Charache; J L Cameron; A W Maters; E I Frantz
Journal:  Ann Surg       Date:  1991-11       Impact factor: 12.969

Review 8.  Occupational risk of human immunodeficiency virus infection in healthcare workers: an overview.

Authors:  D M Bell
Journal:  Am J Med       Date:  1997-05-19       Impact factor: 4.965

9.  Hepatitis B and hepatitis C in emergency department patients.

Authors:  G D Kelen; G B Green; R H Purcell; D W Chan; B F Qaqish; K T Sivertson; T C Quinn
Journal:  N Engl J Med       Date:  1992-05-21       Impact factor: 91.245

10.  Seroprevalence of human immunodeficiency virus-1, hepatitis B virus, and hepatitis C virus in patients having major surgery.

Authors:  M A Montecalvo; M S Lee; H DePalma; P S Wynn; A B Lowenfels; U Jorde; D Wuest; A Klingaman; T A O'Brien; M Calmann
Journal:  Infect Control Hosp Epidemiol       Date:  1995-11       Impact factor: 3.254

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  6 in total

1.  A study of needle stick injuries among non-consultant hospital doctors in Ireland.

Authors:  M B O'Connor; M J Hannon; D Cagney; U Harrington; F O'Brien; N Hardiman; R O'Connor; K Courtney; C O'Connor
Journal:  Ir J Med Sci       Date:  2010-12-29       Impact factor: 1.568

2.  Sharpless surgery: a prospective study of the feasibility of performing operations using non-sharp techniques in an urban, university-based surgical practice.

Authors:  Martin A Makary; Peter J Pronovost; Eric S Weiss; E Anne Millman; David Chang; Susan P Baker; Edward E Cornwell; Dora Syin; Julie A Freischlag
Journal:  World J Surg       Date:  2006-07       Impact factor: 3.352

3.  National Evaluation of Needlestick Events and Reporting Among Surgical Residents.

Authors:  Anthony D Yang; Christopher M Quinn; D Brock Hewitt; Jeanette W Chung; Teresa R Zembower; Andrew Jones; Jo Buyske; David B Hoyt; Thomas J Nasca; Karl Y Bilimoria
Journal:  J Am Coll Surg       Date:  2019-09-18       Impact factor: 6.113

4.  Frequency of Hepatitis-B and C in patients undergoing cataract surgery in a tertiary care Centre.

Authors:  Muhammad Ali Tahir; Alyscia Cheema; Saifullah Tareen
Journal:  Pak J Med Sci       Date:  2015 Jul-Aug       Impact factor: 1.088

5.  Anesthesiologists' acquisition of hepatitis B virus infection: Risk and prevention.

Authors:  Jingling Tian; Fang Tan; Lifei Lai; Yingqing Deng; Xinjin Chi; Hongfang Geng; Qianqian Zhu
Journal:  Medicine (Baltimore)       Date:  2019-07       Impact factor: 1.817

6.  Prevalence of Hepatitis B virus, Hepatitis C virus and human immunodeficiency virus infections among patients candidate for orthopedic trauma surgeries.

Authors:  Ali Yeganeh; Negin Hatami; Mani Mahmoudi; Bahram Boduhi; Mahzad Saidifard; Babak Otoukesh
Journal:  Med J Islam Repub Iran       Date:  2015-10-04
  6 in total

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