Literature DB >> 15844620

Peptide-oligonucleotide conjugates for the delivery of antisense and siRNA.

Rudolph L Juliano1.   

Abstract

Conjugation of oligonucleotides to certain types of peptides provides an interesting approach for enhancing delivery of antisense and siRNA to cells and tissues. This article will provide a perspective on issues in oligonucleotide delivery, and will examine recent literature on the preparation and use of several types of peptide-oligonucleotide conjugates.

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Year:  2005        PMID: 15844620

Source DB:  PubMed          Journal:  Curr Opin Mol Ther        ISSN: 1464-8431


  21 in total

1.  Stepwise synthesis of RNA conjugates carrying peptide sequences for RNA interference studies.

Authors:  Anna Aviñó; Sandra M Ocampo; Clara Caminal; José Carlos Perales; Ramon Eritja
Journal:  Mol Divers       Date:  2009-02-03       Impact factor: 2.943

2.  Tat-conjugated PAMAM dendrimers as delivery agents for antisense and siRNA oligonucleotides.

Authors:  Hyunmin Kang; Robert DeLong; Michael H Fisher; Rudolph L Juliano
Journal:  Pharm Res       Date:  2005-10-01       Impact factor: 4.200

3.  Functional Delivery of siRNA by Disulfide-Constrained Cyclic Amphipathic Peptides.

Authors:  Jade J Welch; Ria J Swanekamp; Christiaan King; David A Dean; Bradley L Nilsson
Journal:  ACS Med Chem Lett       Date:  2016-03-30       Impact factor: 4.345

Review 4.  miRNAs: Key Players in Neurodegenerative Disorders and Epilepsy.

Authors:  Hanuma Kumar Karnati; Manas Kumar Panigrahi; Ravi Kumar Gutti; Nigel H Greig; Ian A Tamargo
Journal:  J Alzheimers Dis       Date:  2015       Impact factor: 4.472

Review 5.  RNAi: a potential new class of therapeutic for human genetic disease.

Authors:  Attila A Seyhan
Journal:  Hum Genet       Date:  2011-05-03       Impact factor: 4.132

Review 6.  Glycotargeting to improve cellular delivery efficiency of nucleic acids.

Authors:  Hongbin Yan; Kha Tram
Journal:  Glycoconj J       Date:  2007-02-01       Impact factor: 2.916

7.  Targeted intracellular delivery of antisense oligonucleotides via conjugation with small-molecule ligands.

Authors:  Osamu Nakagawa; Xin Ming; Leaf Huang; Rudolph L Juliano
Journal:  J Am Chem Soc       Date:  2010-07-07       Impact factor: 15.419

Review 8.  Targeted delivery systems for oligonucleotide therapeutics.

Authors:  Bo Yu; Xiaobin Zhao; L James Lee; Robert J Lee
Journal:  AAPS J       Date:  2009-03-19       Impact factor: 4.009

9.  Cellular delivery and biological activity of antisense oligonucleotides conjugated to a targeted protein carrier.

Authors:  Hyunmin Kang; Md Rowshon Alam; Vidula Dixit; Michael Fisher; Rudy L Juliano
Journal:  Bioconjug Chem       Date:  2008-11-19       Impact factor: 4.774

10.  Peptide-functionalized nanogels for targeted siRNA delivery.

Authors:  William H Blackburn; Erin B Dickerson; Michael H Smith; John F McDonald; L Andrew Lyon
Journal:  Bioconjug Chem       Date:  2009-05-20       Impact factor: 4.774

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