Y Wu1, T Nozaki, T Inamitsu, C Kubo. 1. Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University, Japan. dsyu@cephal.med.kyushu-u.ac.jp
Abstract
OBJECTIVE: The aim of this study was to determine which physical and psychological factors influence the autonomic nervous system (ANS) of patients with anorexia nervosa (AN). METHODS: The subjects were 14 AN patients and 12 healthy controls. Beat to beat heart rate variability recorded in a supine position with a controlled respiratory rate of 15/min, was analyzed using power spectral analysis. Symptoms of anxiety and depression were assessed by State and Trait Anxiety Inventory and Zung's Self-rating Depression Scale respectively. RESULTS: Anxiety had a significant negative correlation with the ANS of AN patients. The illness duration times body mass index (BMI), a measure of sustained extreme loss of weight, was also significantly associated with changes in the ANS of AN patients. CONCLUSION: Although the ANS is influenced by various factors, sustained extreme loss of weight seems to be more influential factor in AN patients.
OBJECTIVE: The aim of this study was to determine which physical and psychological factors influence the autonomic nervous system (ANS) of patients with anorexia nervosa (AN). METHODS: The subjects were 14 AN patients and 12 healthy controls. Beat to beat heart rate variability recorded in a supine position with a controlled respiratory rate of 15/min, was analyzed using power spectral analysis. Symptoms of anxiety and depression were assessed by State and Trait Anxiety Inventory and Zung's Self-rating Depression Scale respectively. RESULTS:Anxiety had a significant negative correlation with the ANS of AN patients. The illness duration times body mass index (BMI), a measure of sustained extreme loss of weight, was also significantly associated with changes in the ANS of AN patients. CONCLUSION: Although the ANS is influenced by various factors, sustained extreme loss of weight seems to be more influential factor in AN patients.
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