Literature DB >> 6166045

Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control.

S Akselrod, D Gordon, F A Ubel, D C Shannon, A C Berger, R J Cohen.   

Abstract

Power spectrum analysis of heart rate fluctuations provides a quantitative noninvasive means of assessing the functioning of the short-term cardiovascular control systems. We show that sympathetic and parasympathetic nervous activity make frequency-specific contributions to the heart rate power spectrum, and that renin-angiotensin system activity strongly modulates the amplitude of the spectral peak located at 0.04 hertz. Our data therefore provide evidence that the renin-angiotensin system plays a significant role in short-term cardiovascular control in the time scale of seconds to minutes.

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Year:  1981        PMID: 6166045     DOI: 10.1126/science.6166045

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  770 in total

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