| Literature DB >> 6166045 |
S Akselrod, D Gordon, F A Ubel, D C Shannon, A C Berger, R J Cohen.
Abstract
Power spectrum analysis of heart rate fluctuations provides a quantitative noninvasive means of assessing the functioning of the short-term cardiovascular control systems. We show that sympathetic and parasympathetic nervous activity make frequency-specific contributions to the heart rate power spectrum, and that renin-angiotensin system activity strongly modulates the amplitude of the spectral peak located at 0.04 hertz. Our data therefore provide evidence that the renin-angiotensin system plays a significant role in short-term cardiovascular control in the time scale of seconds to minutes.Entities:
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Year: 1981 PMID: 6166045 DOI: 10.1126/science.6166045
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728