Literature DB >> 15843744

Theoretical and experimental validation of a dual-frequency excitation method for spatial control of cavitation.

S D Sokka1, T P Gauthier, K Hynynen.   

Abstract

Inertial cavitation has been implicated as the primary mechanism for a host of emerging applications. In all these applications, the main concern is to induce cavitation in perfectly controlled locations in the field; this means specifically to be able to achieve the cavitation threshold at the geometrical focus of the transducer without stimulating its near field. In this study, we develop dual-frequency methods to preferentially lower the cavitation threshold at the focus relative to the rest of the field. Two families of dual-frequency driving waveforms are evaluated in a bubble model incorporating rectified diffusion. Results are then verified by experiment. Finally, the performance of the rest of acoustic field in suppressing cavitation when cavitation is induced at the focus is investigated theoretically and checked experimentally. This study shows that dual-frequency phased arrays could be used to precisely control cavitation. The cavitation threshold is proved to be 1.2 times higher in the near field than at the focus. The concept of cavitation field is introduced and complements cavitation studies concentrating on the focal behaviour only.

Mesh:

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Year:  2005        PMID: 15843744     DOI: 10.1088/0031-9155/50/9/017

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  6 in total

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Journal:  Drug Deliv Transl Res       Date:  2018-02       Impact factor: 4.617

2.  The Effect of Laser and Ultrasound Synchronization in Photo-Mediated Ultrasound Therapy.

Authors:  Yu Qin; Yixin Yu; Xinyi Xie; Wei Zhang; Julia Fu; Yannis M Paulus; Xinmai Yang; Xueding Wang
Journal:  IEEE Trans Biomed Eng       Date:  2020-11-19       Impact factor: 4.538

3.  A multi-frequency sparse hemispherical ultrasound phased array for microbubble-mediated transcranial therapy and simultaneous cavitation mapping.

Authors:  Lulu Deng; Meaghan A O'Reilly; Ryan M Jones; Ran An; Kullervo Hynynen
Journal:  Phys Med Biol       Date:  2016-11-15       Impact factor: 3.609

4.  Closed Loop Spatial and Temporal Control of Cavitation Activity with Passive Acoustic Mapping.

Authors:  Arpit Patel; Scott J Schoen; Costas D Arvanitis
Journal:  IEEE Trans Biomed Eng       Date:  2018-11-20       Impact factor: 4.538

5.  Dual-beam histotripsy: a low-frequency pump enabling a high-frequency probe for precise lesion formation.

Authors:  Kuang-Wei Lin; Alexander P Duryea; Yohan Kim; Timothy L Hall; Zhen Xu; Charles A Cain
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2014-02       Impact factor: 2.725

6.  Dual-Frequency Intravascular Sonothrombolysis: An In Vitro Study.

Authors:  Huaiyu Wu; Leela D Goel; Howuk Kim; Bohua Zhang; Jinwook Kim; Paul A Dayton; Zhen Xu; Xiaoning Jiang
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2021-11-23       Impact factor: 2.725

  6 in total

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