Literature DB >> 15840421

Promoter polymorphism of second tryptophan hydroxylase isoform (TPH2) in schizophrenia and suicidality.

Vincenzo De Luca1, Daphne Voineskos, Gregory W H Wong, Takahiro Shinkai, Claudia Rothe, John Strauss, James L Kennedy.   

Abstract

Allele and haplotype frequencies of a promoter polymorphism in the gene encoding tryptophan hydroxylase (TPH2) did not differ in 83 suicidal schizophrenic patients compared with 170 non-suicidal schizophrenic patients. These findings suggest that these 5' marker haplotypes in the TPH2 gene do not influence suicidal behavior in schizophrenia.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 15840421     DOI： 10.1016/j.psychres.2005.01.005

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  12 in total

1.  Tryptophan-hydroxylase 2 haplotype association with borderline personality disorder and aggression in a sample of patients with personality disorders and healthy controls.

Authors:  M Mercedes Perez-Rodriguez; Shauna Weinstein; Antonia S New; Laura Bevilacqua; Qiaoping Yuan; Zhifeng Zhou; Colin Hodgkinson; Marianne Goodman; Harold W Koenigsberg; David Goldman; Larry J Siever
Journal:  J Psychiatr Res       Date:  2010-05-06       Impact factor: 4.791

Review 2.  Stress, genes and the biology of suicidal behavior.

Authors:  Dianne Currier; J John Mann
Journal:  Psychiatr Clin North Am       Date:  2008-06

3.  Association of polymorphisms in HTR2A, HTR1A and TPH2 genes with suicide attempts in alcohol dependence: a preliminary report.

Authors:  Małgorzata Wrzosek; Jacek Łukaszkiewicz; Michał Wrzosek; Piotr Serafin; Andrzej Jakubczyk; Anna Klimkiewicz; Halina Matsumoto; Kirk J Brower; Marcin Wojnar
Journal:  Psychiatry Res       Date:  2011-05-31       Impact factor: 3.222

4.  Association study of tryptophan hydroxylase-2 gene in schizophrenia and its clinical features in Chinese Han population.

Authors:  Chen Zhang; Zezhi Li; Yang Shao; Bin Xie; Yasong Du; Yiru Fang; Shunying Yu
Journal:  J Mol Neurosci       Date:  2010-10-12       Impact factor: 3.444

Review 5.  Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2.

Authors:  X Zhang; J-M Beaulieu; R R Gainetdinov; M G Caron
Journal:  Cell Mol Life Sci       Date:  2006-01       Impact factor: 9.261

6.  Effect of tryptophan hydroxylase-2 rs7305115 SNP on suicide attempts risk in major depression.

Authors:  Yuqi Zhang; Changsong Zhang; Guozhen Yuan; Jianjun Yao; Zaohuo Cheng; Chaojun Liu; Qinghai Liu; Gairong Wan; Guizhi Shi; Yiren Cheng; Yang Ling; Ke Li
Journal:  Behav Brain Funct       Date:  2010-08-25       Impact factor: 3.759

Review 7.  The role of the serotonergic system at the interface of aggression and suicide.

Authors:  M Bortolato; N Pivac; D Muck Seler; M Nikolac Perkovic; M Pessia; G Di Giovanni
Journal:  Neuroscience       Date:  2013-01-16       Impact factor: 3.590

8.  A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression.

Authors:  Karen L Murphy; Xiaodong Zhang; Raul R Gainetdinov; Jean-Martin Beaulieu; Marc G Caron
Journal:  J Biol Chem       Date:  2008-03-13       Impact factor: 5.157

9.  Associations between prefrontal γ-aminobutyric acid concentration and the tryptophan hydroxylase isoform 2 gene, a panic disorder risk allele in women.

Authors:  Nora Preuss; Basira Salehi; Jan Willem van der Veen; Jun Shen; Wayne C Drevets; Colin Hodgkinson; David Goldman; Gregor Hasler
Journal:  Int J Neuropsychopharmacol       Date:  2013-04-03       Impact factor: 5.176

10.  No association between a TPH2 promoter polymorphism and mood disorders or monoamine turnover.

Authors:  J John Mann; Dianne Currier; Lauren Murphy; Yung-yu Huang; Hanga Galfalvy; David Brent; Laurence Greenhill; Maria Oquendo
Journal:  J Affect Disord       Date:  2007-07-02       Impact factor: 4.839
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.