Literature DB >> 15837415

GCN2 whets the appetite for amino acids.

Thomas E Dever1, Alan G Hinnebusch.   

Abstract

In response to amino acid starvation, the kinase GCN2 in yeast activates amino acid biosynthesis. Two recent studies (Maurin et al., 2005; Hao et al., 2005) reveal that GCN2 in the brain of mice restricts intake of diets lacking essential amino acids.

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Year:  2005        PMID: 15837415     DOI: 10.1016/j.molcel.2005.03.023

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  22 in total

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