| Literature DB >> 15837320 |
Zhi-Qiang Wang1, Jinfang Liao, Zhenjun Diwu.
Abstract
A novel caspase-3 substrate N-Ac-DEVD-N'-MC-R110, which is a fluorogenic substrate cleavable in a single step, has been prepared. It has a significantly higher enzyme turnover rate and sensitivity for detecting caspase-3 activity both in solution and living cells than existing fluorogenic substrates.Entities:
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Year: 2005 PMID： 15837320 DOI： 10.1016/j.bmcl.2005.02.081
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823