Literature DB >> 15827016

Smooth pursuit in patients with downbeat nystagmus.

Stefan Glasauer1, Muna Hoshi, Ulrich Büttner.   

Abstract

Smooth pursuit and gaze holding in light and darkness was investigated in 19 patients with downbeat nystagmus (DBN) and 17 control subjects. Vertical downward smooth pursuit was selectively impaired in patients, and gaze holding with a visible target was only slightly better than in darkness. The selective impairment of downward pursuit and the poor visual suppression of ocular drift in DBN support the involvement of the floccular lobe, which participates in gaze holding and contains gaze-velocity Purkinje cells with a downward on-direction for smooth pursuit.

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Year:  2005        PMID： 15827016     DOI： 10.1196/annals.1325.061

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  10 in total

1.  Current treatment of vestibular, ocular motor disorders and nystagmus.

Authors:  Michael Strupp; Thomas Brandt
Journal:  Ther Adv Neurol Disord       Date:  2009-07       Impact factor: 6.570

2.  Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion.

Authors:  Christoph Helmchen; Stefan Gottschalk; Thurid Sander; Peter Trillenberg; Holger Rambold; Andreas Sprenger
Journal:  J Neurol       Date:  2007-04-06       Impact factor: 4.849

3.  Up-down asymmetry of cerebellar activation during vertical pursuit eye movements.

Authors:  Stefan Glasauer; Thomas Stephan; Roger Kalla; Sarah Marti; Dominik Straumann
Journal:  Cerebellum       Date:  2009-05-05       Impact factor: 3.847

4.  Perverted head impulse test in cerebellar ataxia.

Authors:  Seong-Hae Jeong; Ji-Soo Kim; In Chul Baek; Jong Wook Shin; Hyunjin Jo; Ae Young Lee; Jae-Moon Kim
Journal:  Cerebellum       Date:  2013-10       Impact factor: 3.847

5.  Enhancement of the bias component of downbeat nystagmus after lesions of the nodulus and uvula.

Authors:  Mark F Walker; Jing Tian; Xiaoyan Shan; Howard Ying; Rafael J Tamargo; David S Zee
Journal:  Ann N Y Acad Sci       Date:  2009-05       Impact factor: 5.691

6.  A model-based theory on the origin of downbeat nystagmus.

Authors:  Sarah Marti; Dominik Straumann; Ulrich Büttner; Stefan Glasauer
Journal:  Exp Brain Res       Date:  2008-05-08       Impact factor: 1.972

7.  Lesions of the cerebellar nodulus and uvula impair downward pursuit.

Authors:  Mark F Walker; Jing Tian; Xiaoyan Shan; Rafael J Tamargo; Howard Ying; David S Zee
Journal:  J Neurophysiol       Date:  2008-07-23       Impact factor: 2.714

8.  The ataxic mouse as a model for studying downbeat nystagmus.

Authors:  John S Stahl; Zachary C Thumser; Brian S Oommen
Journal:  J Vestib Res       Date:  2012       Impact factor: 2.435

Review 9.  Pharmacotherapy of vestibular and ocular motor disorders, including nystagmus.

Authors:  Michael Strupp; Matthew J Thurtell; Aasef G Shaikh; Thomas Brandt; David S Zee; R John Leigh
Journal:  J Neurol       Date:  2011-04-02       Impact factor: 4.849

10.  A Variation in FGF14 Is Associated with Downbeat Nystagmus in a Genome-Wide Association Study.

Authors:  Michael Strupp; Stephan Maul; Bettina Konte; Annette M Hartmann; Ina Giegling; Sophia Wollenteit; Katharina Feil; Dan Rujescu
Journal:  Cerebellum       Date:  2020-06       Impact factor: 3.847
  10 in total

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