Literature DB >> 15825424

BRL.8988 (talampicillin), a well-absorbed oral form of ampicillin.

J P Clayton, M Cole, S W Elson, H Ferres.   

Abstract

The phthalidyl ester (BRL.8988, talampicillin) of ampicillin gave serum levels in man two and a half times those obtained with ampicillin itself.

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Year:  1974        PMID： 15825424      PMCID： PMC429033          DOI： 10.1128/AAC.5.6.670

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  4 in total

1.  SOME NOVEL PENICILLIN DERIVATIVES.

Authors:  A B JANSEN; T J RUSSELL
Journal:  J Chem Soc       Date:  1965-03

2.  Acyloxymethyl esters of ampicillin.

Authors:  W Daehne; E Frederiksen; E Gundersen; F Lund; P Morch; H J Petersen; K Roholt; L Tybring; W O Godtfredsen
Journal:  J Med Chem       Date:  1970-07       Impact factor: 7.446

3.  Amoxycillin: a new semi-synthetic penicillin.

Authors:  R Sutherland; E A Croydon; G N Rolinson
Journal:  Br Med J       Date:  1972-07-01

4.  Metabolism of penicillins to penicilloic acids and 6-aminopenicillanic acid in man and its significance in assessing penicillin absorption.

Authors:  M Cole; M D Kenig; V A Hewitt
Journal:  Antimicrob Agents Chemother       Date:  1973-04       Impact factor: 5.191
  4 in total
  10 in total

Review 1.  Lipid-based drug carriers for prodrugs to enhance drug delivery.

Authors:  Jennica L Zaro
Journal:  AAPS J       Date:  2014-10-01       Impact factor: 4.009

2.  Potential improvement in the shelf life of parenterals using the prodrug approach: bacampicillin and talampicillin hydrolysis kinetics and utilization time.

Authors:  N A Nguyen; L M Mortada; R E Notari
Journal:  Pharm Res       Date:  1988-05       Impact factor: 4.200

3.  Potential improvement in shelf life using the prodrug approach. II. A systematic examination of kinetic requirements.

Authors:  N A Nguyen; R E Notari
Journal:  Pharm Res       Date:  1988-10       Impact factor: 4.200

4.  Pharmacokinetic study of lenampicillin (KBT-1585) in healthy volunteers.

Authors:  A Saito; M Nakashima
Journal:  Antimicrob Agents Chemother       Date:  1986-05       Impact factor: 5.191

5.  Bacampicillin: a new orally well-absorbed derivative of ampicillin.

Authors:  N O Bodin; B Ekström; U Forsgren; L P Jalar; L Magni; C H Ramsay; B Sjöberg
Journal:  Antimicrob Agents Chemother       Date:  1975-11       Impact factor: 5.191

6.  Pharmacological and clinical study of bacampicillin in acute peritonsillitis--a comparison with ampicillin.

Authors:  H O Hallander; A Flodström; J Sjövall
Journal:  Antimicrob Agents Chemother       Date:  1977-02       Impact factor: 5.191

7.  Pharmacokinetics of bacampicillin compared with those of ampicillin, pivampicillin, and amoxycillin.

Authors:  J Sjövall; L Magni; T Bergan
Journal:  Antimicrob Agents Chemother       Date:  1978-01       Impact factor: 5.191

8.  Triple crossover study on absorption and excretion of ampicillin, talampicillin, and amoxycillin.

Authors:  L Verbist
Journal:  Antimicrob Agents Chemother       Date:  1976-07       Impact factor: 5.191

9.  Dose dependence in human absorption of aminopenicillins.

Authors:  J Sjövall
Journal:  Infection       Date:  1979       Impact factor: 3.553

10.  Effect of bacampicillin on human mouth, throat and colon flora.

Authors:  A Heimdahl; C E Nord; K Weilander
Journal:  Infection       Date:  1979       Impact factor: 3.553
  10 in total

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