Literature DB >> 15825324

Mutagenic activity of diazoacetylglycine derivatives.

C Monti-Bragadin, M Tamaro, E Banfi.   

Abstract

Some diazoacetyl derivatives of glycine known as antitumor and immunosuppressive agents have been found to be powerful mutagens of the base substitution type.

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Year:  1974        PMID: 15825324      PMCID: PMC444711          DOI: 10.1128/AAC.6.5.655

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  8 in total

1.  An improved bacterial test system for the detection and classification of mutagens and carcinogens.

Authors:  B N Ames; F D Lee; W E Durston
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

2.  Mechanism of inhibition of DNA synthesis in Ehrlich ascites tumour cells by diazoacetyl glycine-amide.

Authors:  T Giraldi; L Baldini
Journal:  Biochem Pharmacol       Date:  1973-07-15       Impact factor: 5.858

3.  Effects of diazoacetyl-glycine amide on purine nucleotide metabolism in Ehrlich ascites tumour cells.

Authors:  T Giraldi; L Baldini
Journal:  Biochem Pharmacol       Date:  1974-01-15       Impact factor: 5.858

4.  The immunodepressive activity of N-diazoacetylglycine amide in some transplantation systems.

Authors:  G Brambilla; S Parodi; M Cavanna; L Baldini
Journal:  Transplantation       Date:  1970-07       Impact factor: 4.939

5.  Effects of diazoacetyl-glycine amide on purine nucleotide and deoxyribonucleic acid synthesis in Ehrlich ascites tumor cells.

Authors:  T Giraldi; G Steppani; L Baldini
Journal:  Biochem Pharmacol       Date:  1972-11-15       Impact factor: 5.858

6.  [Carcinogenic activity of two N-diazoacetyl derivatives of glycine in newborn Swiss mice].

Authors:  G Brambilla; M Cavanna; S Parodi; C E Caraceni
Journal:  Boll Soc Ital Biol Sper       Date:  1970-03-15

7.  Antineoplastic activity of diazoacetyl-glycine derivatives.

Authors:  L Baldini; G Brambilla
Journal:  Cancer Res       Date:  1966-08       Impact factor: 12.701

8.  Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.

Authors:  B N Ames; W E Durston; E Yamasaki; F D Lee
Journal:  Proc Natl Acad Sci U S A       Date:  1973-08       Impact factor: 11.205

  8 in total
  3 in total

1.  Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

Authors:  J McCann; E Choi; E Yamasaki; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

2.  Synthesis and in vitro cytotoxic activity of new n-diazoacetylglycine derivatives.

Authors:  R D Loggia; A Furlani; F Savastano; V Scarcia
Journal:  Experientia       Date:  1976-05-15

3.  DNA damage and repair induced by diazoacetyl derivatives of amino acids with different mechanism of cytotoxicity. Correlations with mutagenicity and carcinogenicity.

Authors:  G Brambilla; M Cavanna; P Carlo; R Finollo; L Sciaba; S Parodi; C Bolognesi
Journal:  J Cancer Res Clin Oncol       Date:  1979-05-14       Impact factor: 4.553

  3 in total

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