Literature DB >> 15822415

Herbal ecstasy: cardiovascular complications of khat chewing in pregnancy.

K M Kuczkowski1.   

Abstract

Chewing fresh leaves of the Khat plant (Catha edulis Celestrasae) is a widespread habit (also practiced by women, even during pregnancy) with a deep-rooted tradition in East Africa and the Arabian Peninsula. With the influx of immigrants from East Africa and the Arabian Peninsula khat chewing has been imported into other countries including Europe the United States. The major pharmacologically active constituent of the fresh khat leaves is cathinone. Khat (also known as herbal ecstasy) is chewed for its central nervous system stimulant properties, which resemble amphetamine. Cardiovascular complications from cathinone use may therefore be similar to those of amphetamine. I herein present the first reported case of a pregnant patient who developed chest pain, tachycardia, and hypertension following khat-chewing session.

Entities:  

Mesh:

Year:  2005        PMID: 15822415

Source DB:  PubMed          Journal:  Acta Anaesthesiol Belg        ISSN: 0001-5164


  7 in total

Review 1.  Drug-induced cardiovascular disorders.

Authors:  C Aengus Murphy; Henry J Dargie
Journal:  Drug Saf       Date:  2007       Impact factor: 5.606

2.  Khat (Catha edulis) chewing during pregnancy in Yemen: findings from a national population survey.

Authors:  Marwan Khawaja; Mohannad Al-Nsour; Ghada Saad
Journal:  Matern Child Health J       Date:  2007-06-06

3.  Khat chewing in pregnant women associated with prelabor rupture of membranes, evidence from eastern Ethiopia.

Authors:  Tesfaye Assebe Yadeta; Gudina Egata; Berhanu Seyoum; Dadi Marami
Journal:  Pan Afr Med J       Date:  2020-05-01

4.  Magnitude of Khat use and associated factors among women attending antenatal care in Gedeo zone health centers, southern Ethiopia: a facility based cross sectional study.

Authors:  Birhanie Mekuriaw; Zelalem Belayneh; Yimenu Yitayih
Journal:  BMC Public Health       Date:  2020-01-28       Impact factor: 3.295

5.  Unraveling the Catha edulis Extract Effects on the Cellular and Molecular Signaling in SKOV3 Cells.

Authors:  Alaa Sayed Abou-Elhamd; Gauthaman Kalamegam; Farid Ahmed; Mourad Assidi; Abdulmajeed Fahad Alrefaei; Peter Natesan Pushparaj; Muhammad Abu-Elmagd
Journal:  Front Pharmacol       Date:  2021-05-10       Impact factor: 5.810

Review 6.  Chemistry, pharmacology, and toxicology of khat (catha edulis forsk): a review.

Authors:  Nasir Tajure Wabe
Journal:  Addict Health       Date:  2011 Summer-Autumn

7.  Sleep disturbances and memory impairment among pregnant women consuming khat: An under-recognized problem.

Authors:  Md Dilshad Manzar; Mohammed Salahuddin; Peter Sony; Tarekegn Tesfaye Maru; Seithikurippu R Pandi-Perumal; Adam Moscovitch; Ahmed S Bahammam
Journal:  Ann Thorac Med       Date:  2017 Oct-Dec       Impact factor: 2.219

  7 in total

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