Y Neria1, E J Bromet, G A Carlson, B Naz. 1. Department of Psychiatry, Columbia University and Anxiety Disorder Clinic, New York State Psychiatric Institute, NY 10032, USA. ny126@columbia.edu
Abstract
OBJECTIVE: Little is known about the relationship of assaultive trauma to clinical and functional outcome in patients with bipolar disorder. METHOD: We assessed trauma histories in a cohort of 109 first-admission bipolar patients with psychosis using structured interviews and medical records. Assaultive trauma included rape, physical attacks, and physical threats. Outcome was assessed using standardized ratings. RESULTS: Forty percent reported a history of assaultive trauma, mostly in childhood (< or =16 years). Exposed patients were more symptomatic at each follow-up than unexposed. Sixteen percent of exposed patients remitted after one episode compared with 38.5% of the non-exposed. Patients exposed as adults were the most symptomatic at 6 months, while patients exposed in childhood were the most symptomatic at 24 months. CONCLUSION: Our findings supported the salient role of trauma history as a risk factor for poor course in severe bipolar disorder. Given the high prevalence of such exposure, clinical awareness in first-admission psychotic bipolar patients is critical. Copyright Blackwell Munksgaard 2005.
OBJECTIVE: Little is known about the relationship of assaultive trauma to clinical and functional outcome in patients with bipolar disorder. METHOD: We assessed trauma histories in a cohort of 109 first-admission bipolarpatients with psychosis using structured interviews and medical records. Assaultive trauma included rape, physical attacks, and physical threats. Outcome was assessed using standardized ratings. RESULTS: Forty percent reported a history of assaultive trauma, mostly in childhood (< or =16 years). Exposed patients were more symptomatic at each follow-up than unexposed. Sixteen percent of exposed patients remitted after one episode compared with 38.5% of the non-exposed. Patients exposed as adults were the most symptomatic at 6 months, while patients exposed in childhood were the most symptomatic at 24 months. CONCLUSION: Our findings supported the salient role of trauma history as a risk factor for poor course in severe bipolar disorder. Given the high prevalence of such exposure, clinical awareness in first-admission psychotic bipolarpatients is critical. Copyright Blackwell Munksgaard 2005.
Authors: Yuval Neria; Mark Olfson; Marc J Gameroff; Priya Wickramaratne; Daniel Pilowsky; Helen Verdeli; Raz Gross; Julián Manetti-Cusa; Randall D Marshall; Rafael Lantigua; Steven Shea; Myrna M Weissman Journal: Bipolar Disord Date: 2008-06 Impact factor: 6.744
Authors: Maria Andreu Pascual; Jessica C Levenson; John Merranko; Mary Kay Gill; Heather Hower; Shirley Yen; Michael Strober; Tina R Goldstein; Benjamin I Goldstein; Neal D Ryan; Lauren M Weinstock; Martin B Keller; David Axelson; Boris Birmaher Journal: J Affect Disord Date: 2020-05-22 Impact factor: 4.839
Authors: Philippe Conus; Sue Cotton; Benno G Schimmelmann; Patrick D McGorry; Martin Lambert Journal: Schizophr Bull Date: 2009-04-21 Impact factor: 9.306
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