PURPOSE: To asses risk factors of proliferative vitreoretinopathy (PVR) and a model for predicting it. METHODS: Observational, case-control. 335 patients with non-complicated retinal detachment (RD) were included: 134 developed PVR (Cases); 201 patients did not (Controls). Risk factors for PVR were identified by multivariate analysis. Influence of variables was assayed according to the surgical approach. By logistic regression analysis a model to predict the risk of developing PVR and odds ratio (OR) values for each clinical factor were estimated. RESULTS: Risk was higher in patients > 70 years and with intraocular pressure lower than 14 (OR: 3.84; CI 95%: 2.04-7.30) and in retinal breaks larger than "1 clock hour" (OR: 2.54; CI: 1.28-5.05), extended retinal detachments (OR: 4.01; CI: 1.98-8.10) and reinterventions (OR: 1.55; CI: 1.14-9.22). Scleral surgery also was a risk factor (OR: 3.89; CI: 2.12-7.14) and aphakia/pseudophakia when scleral surgery is performed (OR: 3.33; CI: 1.54-7.22). A model to predict PVR was proposed with these results. CONCLUSIONS: Surgical approach modifies risk factors of PVR, and should be taken into account to improve the models for predicting it.
PURPOSE: To asses risk factors of proliferative vitreoretinopathy (PVR) and a model for predicting it. METHODS: Observational, case-control. 335 patients with non-complicated retinal detachment (RD) were included: 134 developed PVR (Cases); 201 patients did not (Controls). Risk factors for PVR were identified by multivariate analysis. Influence of variables was assayed according to the surgical approach. By logistic regression analysis a model to predict the risk of developing PVR and odds ratio (OR) values for each clinical factor were estimated. RESULTS: Risk was higher in patients > 70 years and with intraocular pressure lower than 14 (OR: 3.84; CI 95%: 2.04-7.30) and in retinal breaks larger than "1 clock hour" (OR: 2.54; CI: 1.28-5.05), extended retinal detachments (OR: 4.01; CI: 1.98-8.10) and reinterventions (OR: 1.55; CI: 1.14-9.22). Scleral surgery also was a risk factor (OR: 3.89; CI: 2.12-7.14) and aphakia/pseudophakia when scleral surgery is performed (OR: 3.33; CI: 1.54-7.22). A model to predict PVR was proposed with these results. CONCLUSIONS: Surgical approach modifies risk factors of PVR, and should be taken into account to improve the models for predicting it.
Authors: Michele Reibaldi; Andrea Russo; Antonio Longo; Vincenza Bonfiglio; Maurizio G Uva; Caterina Gagliano; Mario D Toro; Teresio Avitabile Journal: Case Rep Ophthalmol Date: 2013-04-24
Authors: Salvatore Di Lauro; Melissa Castrejón; Itziar Fernández; Jimena Rojas; Rosa M Coco; María R Sanabria; Enrique Rodríguez de la Rua; J Carlos Pastor Journal: J Ophthalmol Date: 2015-11-12 Impact factor: 1.909
Authors: J Carlos Pastor; Itziar Fernández; Rosa M Coco; María R Sanabria; Enrique Rodríguez de la Rúa; Rosa M Piñon; Vicente Martinez; Anna Sala-Puigdollers; José M Gallardo; Sara Velilla Journal: ISRN Ophthalmol Date: 2012-10-08
Authors: Salvador Pastor-Idoate; Irene Rodríguez-Hernández; Jimena Rojas; Itziar Fernández; María T García-Gutiérrez; José M Ruiz-Moreno; Amandio Rocha-Sousa; Yashin Ramkissoon; Steven Harsum; Robert E MacLaren; David Charteris; Jan C VanMeurs; Rogelio González-Sarmiento; José C Pastor Journal: PLoS One Date: 2013-12-09 Impact factor: 3.240