Literature DB >> 15809027

Linking epithelial-mesenchymal transition to the well-known polarity protein Par6.

Jean Paul Thiery1, Ruby Huang.   

Abstract

Epithelial-mesenchymal transition (EMT) is involved in the formation of the body plan, tissue remodeling, and cancer progression. Two recent reports in Science (Barrios-Rodiles et al., 2005; Ozdamar et al., 2005) have decisively advanced our understanding of EMT. Par6 was identified as a key player in the control of tight junction (TJ) stability. This new study provides further insight into the protein networks involved in topologically regulated control of epithelial cell polarity and plasticity.

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Year:  2005        PMID： 15809027     DOI： 10.1016/j.devcel.2005.03.002

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  15 in total

Review 1.  Cell polarity in motion: redefining mammary tissue organization through EMT and cell polarity transitions.

Authors:  Nathan J Godde; Ryan C Galea; Imogen A Elsum; Patrick O Humbert
Journal:  J Mammary Gland Biol Neoplasia       Date:  2010-05-12       Impact factor: 2.673

2.  Numb: A new player in EMT.

Authors:  Zezhou Wang; Shawn S-C Li
Journal:  Cell Adh Migr       Date:  2010-04-16       Impact factor: 3.405

3.  Derlin-dependent retrograde transport from endosomes to the Golgi apparatus.

Authors:  Hope Dang; Tove I Klokk; Basil Schaheen; Brooke M McLaughlin; Anthony J Thomas; Tyler A Durns; Benjamin G Bitler; Kirsten Sandvig; Hanna Fares
Journal:  Traffic       Date:  2011-07-27       Impact factor: 6.215

4.  Atypical protein kinase C phosphorylates Par6 and facilitates transforming growth factor β-induced epithelial-to-mesenchymal transition.

Authors:  Adrian Gunaratne; Boun L Thai; Gianni M Di Guglielmo
Journal:  Mol Cell Biol       Date:  2012-12-17       Impact factor: 4.272

Review 5.  The basics of epithelial-mesenchymal transition.

Authors:  Raghu Kalluri; Robert A Weinberg
Journal:  J Clin Invest       Date:  2009-06       Impact factor: 14.808

6.  The prognostic impact of TGF-β1, fascin, NF-κB and PKC-ζ expression in soft tissue sarcomas.

Authors:  Andrej Valkov; Sveinung W Sorbye; Thomas K Kilvaer; Tom Donnem; Eivind Smeland; Roy M Bremnes; Lill-Tove Busund
Journal:  PLoS One       Date:  2011-03-03       Impact factor: 3.240

7.  Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity.

Authors:  Robert Strauss; Zong-Yi Li; Ying Liu; Ines Beyer; Jonas Persson; Pavel Sova; Thomas Möller; Sari Pesonen; Akseli Hemminki; Petra Hamerlik; Charles Drescher; Nicole Urban; Jiri Bartek; André Lieber
Journal:  PLoS One       Date:  2011-01-14       Impact factor: 3.240

8.  A comparison of stem cell-related gene expression in the progenitor-rich limbal epithelium and the differentiating central corneal epithelium.

Authors:  Teresa Nieto-Miguel; Margarita Calonge; Ana de la Mata; Marina López-Paniagua; Sara Galindo; María Fideliz de la Paz; Rosa M Corrales
Journal:  Mol Vis       Date:  2011-08-10       Impact factor: 2.367

9.  Expression and significance of c-kit and epithelial-mesenchymal transition (EMT) molecules in thymic epithelial tumors (TETs).

Authors:  Zhigang Wu; Songtao Xue; Bin Zheng; Rongjin Ye; Guobing Xu; Shuliang Zhang; Taidui Zeng; Wei Zheng; Chun Chen
Journal:  J Thorac Dis       Date:  2019-11       Impact factor: 2.895

10.  The prognostic impact of NF-kappaB p105, vimentin, E-cadherin and Par6 expression in epithelial and stromal compartment in non-small-cell lung cancer.

Authors:  S Al-Saad; K Al-Shibli; T Donnem; M Persson; R M Bremnes; L-T Busund
Journal:  Br J Cancer       Date:  2008-10-14       Impact factor: 7.640
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