| Literature DB >> 15808483 |
Dooseop Kim1, Liping Wang, Jeffrey J Hale, Christopher L Lynch, Richard J Budhu, Malcolm Maccoss, Sander G Mills, Lorraine Malkowitz, Sandra L Gould, Julie A DeMartino, Martin S Springer, Daria Hazuda, Michael Miller, Joseph Kessler, Renee C Hrin, Gwen Carver, Anthony Carella, Karen Henry, Janet Lineberger, William A Schleif, Emilio A Emini.
Abstract
A series of 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists containing a variety of fused heterocycles at the 4-position of the piperidine side chain has been discovered, which are orally bioavailable with potent anti-HIV activity.Entities:
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Year: 2005 PMID： 15808483 DOI： 10.1016/j.bmcl.2005.02.030
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823