BACKGROUND: Rosai-Dorfman disease (RDD) is a benign, rare, histiocytic disorder of unknown etiology. We describe the case of a 61-year-old woman who presented to the ophthalmology clinic with bilateral granulomatous anterior uveitis. METHODS: The uveitis was controlled on topical prednisolone acetate 1%. One month after presentation, she developed generalized macules and papules, and dermatologic and systemic evaluations were performed. RESULTS: On the basis of skin biopsy, purely cutaneous RDD was established. CONCLUSION: Anterior granulomatous uveitis may be the presenting sign of cutaneous RDD. Consultation is necessary for accurate diagnosis.
BACKGROUND:Rosai-Dorfman disease (RDD) is a benign, rare, histiocytic disorder of unknown etiology. We describe the case of a 61-year-old woman who presented to the ophthalmology clinic with bilateral granulomatous anterior uveitis. METHODS: The uveitis was controlled on topical prednisolone acetate 1%. One month after presentation, she developed generalized macules and papules, and dermatologic and systemic evaluations were performed. RESULTS: On the basis of skin biopsy, purely cutaneous RDD was established. CONCLUSION:Anterior granulomatous uveitis may be the presenting sign of cutaneous RDD. Consultation is necessary for accurate diagnosis.
Authors: Thomas Brenn; Eduardo Calonje; Scott R Granter; Niamh Leonard; Wayne Grayson; Christopher D M Fletcher; Phillip H McKee Journal: Am J Dermatopathol Date: 2002-10 Impact factor: 1.533
Authors: P Pivetti-Pezzi; C Torce; R A Colabelli-Gisoldi; A Vitale; A Baccari; A Pacchiarotti Journal: Eur J Ophthalmol Date: 1995 Jan-Mar Impact factor: 1.922