Literature DB >> 15803433

How do thiazide and thiazide-like diuretics lower blood pressure?

Alun D Hughes1.   

Abstract

Thiazide diuretics are widely used for the treatment of hypertension, but the mechanism by which these drugs lower blood pressure in the long term remains unknown. This article reviews current knowledge about the hypotensive actions of thiazides and thiazide-like diuretics and discusses possible mechanisms of action.

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Year:  2004        PMID： 15803433     DOI： 10.3317/jraas.2004.034

Source DB:  PubMed          Journal:  J Renin Angiotensin Aldosterone Syst        ISSN： 1470-3203            Impact factor:   1.636


  24 in total

Review 1.  Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics.

Authors:  Julio D Duarte; Rhonda M Cooper-DeHoff
Journal:  Expert Rev Cardiovasc Ther       Date:  2010-06

Review 2.  Dihydropyridine calcium channel antagonists in the management of hypertension.

Authors:  Benjamin J Epstein; Katherine Vogel; Biff F Palmer
Journal:  Drugs       Date:  2007       Impact factor: 9.546

Review 3.  Do thiazides worsen metabolic syndrome and renal disease? The pivotal roles for hyperuricemia and hypokalemia.

Authors:  Sirirat Reungjui; Thongchai Pratipanawatr; Richard J Johnson; Takahiko Nakagawa
Journal:  Curr Opin Nephrol Hypertens       Date:  2008-09       Impact factor: 2.894

Review 4.  Thiazide effects and adverse effects: insights from molecular genetics.

Authors:  David H Ellison; Johannes Loffing
Journal:  Hypertension       Date:  2009-06-29       Impact factor: 10.190

5.  Lack of thiazide diuretic inhibition of agonist constriction of mouse mesenteric arterioles ex vivo.

Authors:  Robert M Rapoport; Amanda J LeBlanc; Jason E Beare; Manoocher Soleimani
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2018-11-23       Impact factor: 3.000

Review 6.  Thiazide Diuretics in Chronic Kidney Disease.

Authors:  Arjun D Sinha; Rajiv Agarwal
Journal:  Curr Hypertens Rep       Date:  2015-03       Impact factor: 5.369

Review 7.  Chlorthalidone: mechanisms of action and effect on cardiovascular events.

Authors:  George C Roush; Venkata Buddharaju; Michael E Ernst; Theodore R Holford
Journal:  Curr Hypertens Rep       Date:  2013-10       Impact factor: 5.369

Review 8.  Pharmacotherapy for hypertension in adults aged 18 to 59 years.

Authors:  Vijaya M Musini; Francois Gueyffier; Lorri Puil; Douglas M Salzwedel; James M Wright
Journal:  Cochrane Database Syst Rev       Date:  2017-08-16

Review 9.  Thiazide and thiazide-like diuretics: an opportunity to reduce blood pressure in patients with advanced kidney disease.

Authors:  Feras Karadsheh; Matthew R Weir
Journal:  Curr Hypertens Rep       Date:  2012-10       Impact factor: 5.369

10.  Differential effect of low dose thiazides on the Renin Angiotensin system in genetically hypertensive and normotensive rats.

Authors:  Jewell A Jessup; K Bridget Brosnihan; Patricia E Gallagher; Mark C Chappell; Carlos M Ferrario
Journal:  J Am Soc Hypertens       Date:  2008 Mar-Apr
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