Literature DB >> 15800156

The longitudinal course of thought disorder in geriatric patients with chronic schizophrenia.

Christopher R Bowie1, Irene Tsapelas, Joseph Friedman, Michael Parrella, Leonard White, Philip D Harvey.   

Abstract

OBJECTIVE: This study longitudinally assessed previously validated dimensions of thought disorder--verbal underproductivity and disconnection--in geriatric schizophrenia and replicated previous cross-sectional differences in communication disorders.
METHOD: Two hundred twenty patients with chronic schizophrenia were assessed with the Thought, Language, and Communication Scale over a mean follow-up period of 2.3 years.
RESULTS: Patients had increases in verbal underproductivity but stable scores on disconnection over the follow-up period. Worsening in verbal underproductivity was associated with concurrent worsening in Mini-Mental State Examination scores and older age at baseline.
CONCLUSIONS: Verbal underproductivity worsens with aging and is associated with cognitive worsening, although disconnected speech is relatively stable. Some geriatric patients with schizophrenia may lose the skills necessary to report symptoms, leading to the impression that their clinical status is improving.

Entities:  

Mesh:

Year:  2005        PMID: 15800156     DOI: 10.1176/appi.ajp.162.4.793

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  8 in total

1.  Thought, language, and communication deficits and association with everyday functional outcomes among community-dwelling middle-aged and older adults with schizophrenia.

Authors:  Anjana Muralidharan; Anastasia Finch; Christopher R Bowie; Philip D Harvey
Journal:  Schizophr Res       Date:  2017-08-01       Impact factor: 4.939

Review 2.  Very poor outcome schizophrenia: clinical and neuroimaging aspects.

Authors:  Serge A Mitelman; Monte S Buchsbaum
Journal:  Int Rev Psychiatry       Date:  2007-08

3.  Cognitive control components and speech symptoms in people with schizophrenia.

Authors:  Theresa M Becker; David C Cicero; Nelson Cowan; John G Kerns
Journal:  Psychiatry Res       Date:  2012-02-22       Impact factor: 3.222

Review 4.  The Epidemiology and Associated Phenomenology of Formal Thought Disorder: A Systematic Review.

Authors:  Eric Roche; Lisa Creed; Donagh MacMahon; Daria Brennan; Mary Clarke
Journal:  Schizophr Bull       Date:  2014-09-01       Impact factor: 9.306

5.  Quantifying incoherence in speech: an automated methodology and novel application to schizophrenia.

Authors:  Brita Elvevåg; Peter W Foltz; Daniel R Weinberger; Terry E Goldberg
Journal:  Schizophr Res       Date:  2007-04-16       Impact factor: 4.939

6.  Communication abnormalities predict functional outcomes in chronic schizophrenia: differential associations with social and adaptive functions.

Authors:  Christopher R Bowie; Philip D Harvey
Journal:  Schizophr Res       Date:  2008-06-20       Impact factor: 4.939

7.  Latent semantic variables are associated with formal thought disorder and adaptive behavior in older inpatients with schizophrenia.

Authors:  Katherine Holshausen; Philip D Harvey; Brita Elvevåg; Peter W Foltz; Christopher R Bowie
Journal:  Cortex       Date:  2013-02-19       Impact factor: 4.027

8.  Psychotropic drug-prescribing correlates of disorganized speech in Asians with schizophrenia: The REAP-AP study.

Authors:  Yong Chon Park; Min-Soo Lee; Tian-Mei Si; Helen F K Chiu; Shigenobu Kanba; Mian-Yoon Chong; Adarsh Tripathi; Pichet Udomratn; Kok Yoon Chee; Andi J Tanra; Golam Rabbani; Afzal Javed; Samudra Kathiarachchi; Win Aung Myint; Tran Van Cuong; Kang Sim; Shu-Yu Yang; Norman Sartorius; Chay-Hoon Tan; Naotaka Shinfuku; Seon-Cheol Park
Journal:  Saudi Pharm J       Date:  2018-11-13       Impact factor: 4.330

  8 in total

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