Literature DB >> 15793164

In vitro and in vivo cytotoxicities and antileishmanial activities of thymol and hemisynthetic derivatives.

Sara Robledo1, Edison Osorio, Diana Muñoz, Luz Marina Jaramillo, Adriana Restrepo, Gabriel Arango, Iván Vélez.   

Abstract

The in vitro and in vivo antileishmanial and cytotoxic activities of thymol and structural derivatives in comparison to those of Glucantime were studied. The results showed here suggest that thymol and hemisynthetic derivatives have promising antileishmanial potential and could be considered as new lead structures in the search for novel antileishmanial drugs.

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Year:  2005        PMID： 15793164      PMCID： PMC1068650          DOI： 10.1128/AAC.49.4.1652-1655.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  17 in total

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