Literature DB >> 15787617

Using proteomics to identify potential therapeutic targets in platelets.

P B Maguire1, M Foy, D J Fitzgerald.   

Abstract

Proteomics has provided powerful new insights into the complex events of the anucleate platelet and has revealed many potential protein targets in the search for suitable agents for thrombotic disease. In the present study, we summarize recent proteomic approaches to analyse specific platelet subproteomes, such as the platelet releasate, the platelet phosphotyrosine proteome and characterization of the proteins associated with membrane lipid rafts.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 15787617     DOI: 10.1042/BST0330409

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN: 0300-5127            Impact factor:   5.407


  6 in total

1.  Scavenger receptor BI modulates platelet reactivity and thrombosis in dyslipidemia.

Authors:  Yi Ma; Mohammad Z Ashraf; Eugene A Podrez
Journal:  Blood       Date:  2010-05-27       Impact factor: 22.113

Review 2.  Platelet genomics and proteomics in human health and disease.

Authors:  Iain C Macaulay; Philippa Carr; Arief Gusnanto; Willem H Ouwehand; Des Fitzgerald; Nicholas A Watkins
Journal:  J Clin Invest       Date:  2005-12       Impact factor: 14.808

Review 3.  Proteomic approaches to dissect platelet function: Half the story.

Authors:  Dmitri V Gnatenko; Peter L Perrotta; Wadie F Bahou
Journal:  Blood       Date:  2006-08-22       Impact factor: 22.113

Review 4.  The genetics of common variation affecting platelet development, function and pharmaceutical targeting.

Authors:  A D Johnson
Journal:  J Thromb Haemost       Date:  2011-07       Impact factor: 5.824

Review 5.  The platelet proteome.

Authors:  Lisa Senzel; Dmitri V Gnatenko; Wadie F Bahou
Journal:  Curr Opin Hematol       Date:  2009-09       Impact factor: 3.284

6.  Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3.

Authors:  Naohide Watanabe; Laurent Bodin; Manjula Pandey; Matthias Krause; Shaun Coughlin; Vassiliki A Boussiotis; Mark H Ginsberg; Sanford J Shattil
Journal:  J Cell Biol       Date:  2008-06-23       Impact factor: 10.539

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.