Literature DB >> 15787594

Trifluoroacetic acid-mediated hydroarylation: synthesis of dihydrocoumarins and dihydroquinolones.

Kelin Li1, Lindsay N Foresee, Jon A Tunge.   

Abstract

[reaction: see text] Trifluoroacetic acid mediates the hydroarylation of alkenes to afford dihydrocoumarins and dihydroquinolones in good yield. Intermolecular hydroarylation of cinnamic acids by phenols is particularly facile, which leads to the conclusion that previous reports of palladium-catalyzed hydroarylation of cinnamic acids in trifluoroacetic acid are erroneous.

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Year:  2005        PMID: 15787594     DOI: 10.1021/jo0477650

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  11 in total

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Journal:  Mol Divers       Date:  2010-07-29       Impact factor: 2.943

2.  Synthesis and Preliminary Biological Study of Bisindolylmethanes Accessed by an Acid-Catalyzed Hydroarylation of Vinylindoles.

Authors:  Tejas P Pathak; Jaroslaw G Osiak; Rachel M Vaden; Bryan E Welm; Matthew S Sigman
Journal:  Tetrahedron       Date:  2012-07-01       Impact factor: 2.457

3.  Small molecule amides as potent ROR-γ selective modulators.

Authors:  Pasha M Khan; Bahaa El-Dien M El-Gendy; Naresh Kumar; Ruben Garcia-Ordonez; Li Lin; Claudia H Ruiz; Michael D Cameron; Patrick R Griffin; Theodore M Kamenecka
Journal:  Bioorg Med Chem Lett       Date:  2012-11-22       Impact factor: 2.823

4.  Stereochemical control in the reduction of 2-chromanols.

Authors:  Kelin Li; Kumar Vanka; Ward H Thompson; Jon A Tunge
Journal:  Org Lett       Date:  2006-10-12       Impact factor: 6.005

5.  Synthesis, characterization, and computational study of the supramolecular arrangement of a novel cinnamic acid derivative.

Authors:  S S Oliveira; L G Santin; L R Almeida; L A Malaspina; C Lariucci; J F Silva; W B Fernandes; G L B Aquino; R Gargano; A J Camargo; H B Napolitano
Journal:  J Mol Model       Date:  2017-01-24       Impact factor: 1.810

6.  Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors.

Authors:  Jun R Huh; Erika E Englund; Hang Wang; Ruili Huang; Pengxiang Huang; Fraydoon Rastinejad; James Inglese; Christopher P Austin; Ronald L Johnson; Wenwei Huang; Dan R Littman
Journal:  ACS Med Chem Lett       Date:  2013-01-10       Impact factor: 4.345

7.  Lewis acid-catalyzed diastereoselective hydroarylation of benzylidene malonic esters.

Authors:  Shaofeng Duan; Ranjan Jana; Jon A Tunge
Journal:  J Org Chem       Date:  2009-06-19       Impact factor: 4.354

8.  rac-(1S,2R)-Diethyl 6-hydr-oxy-1-(4-methoxy-phen-yl)-3-oxo-2,3-di-hydro-1H-benzo[f]chromen-2-yl]-phospho-nate.

Authors:  Jakub Wojciechowski; Henryk Krawczyk; Lukasz Albrecht; Wojciech M Wolf
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-06-07

9.  A novel method for the synthesis of substituted 3,4-dihydrocoumarin derivatives via isocyanide-based three-component reaction.

Authors:  Ahmad Shaabani; Afshin Sarvary; Ebrahim Soleimani; Ali Hossein Rezayan; Marjan Heidary
Journal:  Mol Divers       Date:  2008-10-01       Impact factor: 2.943

10.  Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma.

Authors:  Trevor J Grant; Joshua A Bishop; Lisa M Christadore; Girish Barot; Hang Gyeong Chin; Sarah Woodson; John Kavouris; Ayesha Siddiq; Rachel Gredler; Xue-Ning Shen; Jennifer Sherman; Tracy Meehan; Kevin Fitzgerald; Sriharsa Pradhan; Laura A Briggs; William H Andrews; Devanand Sarkar; Scott E Schaus; Ulla Hansen
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-06       Impact factor: 11.205

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