OBJECTIVE: To verify the result in the use of intratympanic corticosteroids, combined with intravenous, in patients with Meniere disease (MD). MATERIAL AND METHODS: Ten patients with vertigo due to MD in stages 4-5 or 6 were included in the study. Combined intratympanic and intravenous dexamethasone was infiltrated. The number of episodes among the months 18 and 24 of treatment, comparing them with the number of episodes 6 months before treatment (according to the norms of the American committee for the hearing and the equilibrium, 1995) are studied. RESULTS: All patients improved significantly. In one of them treatment was repeated after 6 months. A number of patients with hearing improvement were observed. CONCLUSIONS: The use of combined dexamethasone may be useful to control vertigo due to MD, to avoid or to be a prior step to other more aggressive treatments.
OBJECTIVE: To verify the result in the use of intratympanic corticosteroids, combined with intravenous, in patients with Meniere disease (MD). MATERIAL AND METHODS: Ten patients with vertigo due to MD in stages 4-5 or 6 were included in the study. Combined intratympanic and intravenous dexamethasone was infiltrated. The number of episodes among the months 18 and 24 of treatment, comparing them with the number of episodes 6 months before treatment (according to the norms of the American committee for the hearing and the equilibrium, 1995) are studied. RESULTS: All patients improved significantly. In one of them treatment was repeated after 6 months. A number of patients with hearing improvement were observed. CONCLUSIONS: The use of combined dexamethasone may be useful to control vertigo due to MD, to avoid or to be a prior step to other more aggressive treatments.
Authors: B Fattori; A Nacci; A Dardano; I Dallan; M Grosso; C Traino; V Mancini; F Ursino; F Monzani Journal: Clin Exp Immunol Date: 2008-01-28 Impact factor: 4.330