PURPOSE: To test the feasibility of performing magnetic resonance (MR)-guided trans-septal punctures in the swine heart. MATERIALS AND METHODS: All procedures were performed in a 1.5-T MR scanner. A novel, active MR intravascular needle system was utilized for needle tracking and septal punctures. Trans-septal punctures were performed in five swine using electrocardiogram (ECG)-gated high resolution and non-ECG-gated, real-time MR imaging techniques. The intravascular needle was advanced over a guidewire from the femoral vein. Once the needle was in proper position, trans-septal punctures were made. RESULTS: Active tracking of the needle traversing the septum was possible. The location of the catheter tip was confirmed using real time gradient recalled echo (GRE). After a confirmatory ventriculogram with gadolinium-DTPA, a 0.014-inch guidewire was advanced into the left atrium and left ventricle. All punctures were made with no change in cardiac rhythm or rate; postmortem analysis was performed on all animals and demonstrated that 18/19 (95%) punctures were directly through the fossa ovalis. CONCLUSION: Using only MR guidance and a novel active intravascular needle system, we were able to repeatedly puncture the fossa ovalis in a swine heart from a transfemoral approach, with direct visualization of all components, including the needle, the atria, the fossa ovalis, and the surrounding vasculature. Copyright 2005 Wiley-Liss, Inc.
PURPOSE: To test the feasibility of performing magnetic resonance (MR)-guided trans-septal punctures in the swine heart. MATERIALS AND METHODS: All procedures were performed in a 1.5-T MR scanner. A novel, active MR intravascular needle system was utilized for needle tracking and septal punctures. Trans-septal punctures were performed in five swine using electrocardiogram (ECG)-gated high resolution and non-ECG-gated, real-time MR imaging techniques. The intravascular needle was advanced over a guidewire from the femoral vein. Once the needle was in proper position, trans-septal punctures were made. RESULTS: Active tracking of the needle traversing the septum was possible. The location of the catheter tip was confirmed using real time gradient recalled echo (GRE). After a confirmatory ventriculogram with gadolinium-DTPA, a 0.014-inch guidewire was advanced into the left atrium and left ventricle. All punctures were made with no change in cardiac rhythm or rate; postmortem analysis was performed on all animals and demonstrated that 18/19 (95%) punctures were directly through the fossa ovalis. CONCLUSION: Using only MR guidance and a novel active intravascular needle system, we were able to repeatedly puncture the fossa ovalis in a swine heart from a transfemoral approach, with direct visualization of all components, including the needle, the atria, the fossa ovalis, and the surrounding vasculature. Copyright 2005 Wiley-Liss, Inc.
Authors: Amish N Raval; Parag V Karmarkar; Michael A Guttman; Cengizhan Ozturk; Ranil Desilva; Ronnier J Aviles; Victor J Wright; William H Schenke; Ergin Atalar; Elliot R McVeigh; Robert J Lederman Journal: Catheter Cardiovasc Interv Date: 2006-04 Impact factor: 2.692
Authors: Amish N Raval; Parag V Karmarkar; Michael A Guttman; Cengizhan Ozturk; Smita Sampath; Ranil DeSilva; Ronnier J Aviles; Minnan Xu; Victor J Wright; William H Schenke; Ozgur Kocaturk; Alexander J Dick; Venkatesh K Raman; Ergin Atalar; Elliot R McVeigh; Robert J Lederman Journal: Circulation Date: 2006-02-20 Impact factor: 29.690
Authors: Akbar Alipour; Eric S Meyer; Charles L Dumoulin; Ronald D Watkins; Hassan Elahi; Wolfgang Loew; Jeffrey Schweitzer; Gregory Olson; Yue Chen; Susumu Tao; Michael Guttman; Aravindan Kolandaivelu; Henry R Halperin; Ehud J Schmidt Journal: IEEE Trans Biomed Eng Date: 2019-09-13 Impact factor: 4.538