Literature DB >> 15776145

[Intra-articular treatment with Hylan G-F 20 under ultrasound guidance in hip osteoarthritis. Clinical results after 12 months follow-up].

A Migliore1, S Tormenta, C Valente, U Massafra, L S Martin Martin, E Carmenini, A Bernardini, A Alimonti.   

Abstract

Hip is a site very commonly affected by osteoarthritis (OA), yet few data exist in literature regarding intra-articular use of hyaluronic acid in this pathology. We evaluated the efficacy of Hylan G-F 20 hip viscosupplementation performed under ultrasound guidance. We enrolled 26 patients affected by symptomatic hip OA and treated them with a single intraarticular injection of Hylan G-F 20, which could be repeated every two months. The injection was performed under ultrasound guidance with an antero-superior approach. Treatment efficacy was assessed through Lequesne index, visual analogue scale (VAS) pain quantification, and NSAID intake at the timepoint zero (baseline), and after 2, 6 and 12 months. We observed a statistically significant reduction of all considered parameters at the timepoints 2 and 6 months, when compared to baseline. At 12 months the changes were still statistically significant for all parameters for about 50% of the patients. No side effect was observed, nor systemic complication. Viscosupplementation is a promising approach for hip OA, although further and wider studies are wanted to determine how long the beneficial effect lasts, and what is the optimal number of injections to administer.

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Year:  2005        PMID: 15776145     DOI: 10.4081/reumatismo.2005.36

Source DB:  PubMed          Journal:  Reumatismo        ISSN: 0048-7449


  6 in total

1.  Image quality of hip MR arthrography with intra-articular injection of hyaluronic acid versus gadolinium-based contrast agent in patients with femoroacetabular impingement.

Authors:  Filippo Randelli; Elisabetta Antonia Nocerino; Luca Nicosia; Marco Alì; Caterina Beatrice Monti; Francesco Sardanelli; Alberto Aliprandi
Journal:  Skeletal Radiol       Date:  2020-01-08       Impact factor: 2.199

2.  Hylan g-f 20: review of its safety and efficacy in the management of joint pain in osteoarthritis.

Authors:  A Migliore; F Giovannangeli; M Granata; B Laganà
Journal:  Clin Med Insights Arthritis Musculoskelet Disord       Date:  2010-09-20

3.  Differences Regarding Branded HA in Italy, Part 2: Data from Clinical Studies on Knee, Hip, Shoulder, Ankle, Temporomandibular Joint, Vertebral Facets, and Carpometacarpal Joint.

Authors:  A Migliore; E Bizzi; O De Lucia; A Delle Sedie; S Tropea; M Bentivegna; A Mahmoud; C Foti
Journal:  Clin Med Insights Arthritis Musculoskelet Disord       Date:  2016-06-07

4.  Molecular Weight of Hyaluronic Acid Has Major Influence on Its Efficacy and Safety for Viscosupplementation in Hip Osteoarthritis: A Systematic Review and Meta-Analysis.

Authors:  Yen-Zung Wu; Hsuan-Ti Huang; Cheng-Jung Ho; Chia-Lung Shih; Chung-Hwan Chen; Tsung-Lin Cheng; Ying-Chun Wang; Sung-Yen Lin
Journal:  Cartilage       Date:  2021-06-10       Impact factor: 3.117

5.  Viscosupplementation in the hip: evaluation of hyaluronic acid formulations.

Authors:  M P J van den Bekerom; B Rys; M Mulier
Journal:  Arch Orthop Trauma Surg       Date:  2007-06-16       Impact factor: 3.067

Review 6.  Intra-articular use of hyaluronic acid in the treatment of osteoarthritis.

Authors:  Alberto Migliore; Mauro Granata
Journal:  Clin Interv Aging       Date:  2008       Impact factor: 4.458

  6 in total

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