Literature DB >> 15774898

Soj antagonizes Spo0A activation of transcription in Bacillus subtilis.

Brett N McLeod1, George B Spiegelman.   

Abstract

The ParA family protein Soj appears to negatively regulate sporulation in Bacillus subtilis by inhibiting transcription from promoters that are activated by phosphorylated Spo0A. We tested in vitro Soj inhibition of Spo0A-independent variants of a promoter that Soj inhibited (PspoIIG). Transcription from the variants was less sensitive to Soj inhibition, suggesting that inhibition of wild-type PspoIIG was linked to transcription activation by Spo0A.

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Year:  2005        PMID: 15774898      PMCID: PMC1065239          DOI: 10.1128/JB.187.7.2532-2536.2005

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  28 in total

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