| Literature DB >> 15772297 |
Ingrid Fleming1, Karin Kohlstedt, Rudi Busse.
Abstract
Inhibition of the angiotensin-converting enzyme (ACE) protects against the progression of several cardiovascular diseases. Recent evidence suggests that some of the beneficial effects of ACE inhibitors can be attributed to the activation of a distinct ACE signaling cascade rather than to the changes in angiotensin II and bradykinin levels. Moreover, at least one other ACE homolog (ACE2) plays a significant role in the regulation of heart and kidney function.Entities:
Mesh:
Substances:
Year: 2005 PMID: 15772297 DOI: 10.1152/physiol.00003.2005
Source DB: PubMed Journal: Physiology (Bethesda) ISSN: 1548-9221