| Literature DB >> 15771680 |
R J Quinnell1, J Bethony, D I Pritchard.
Abstract
Advances in hookworm immunoepidemiology are reviewed. Recent studies demonstrate a mixed Th1/Th2 response in human hookworm infection, with immunosuppression of specific and nonspecific IFN-gamma responses. There is increasing evidence for protective immunity in human hookworm infection, including anti-larval IL-5- and IgE-dependent mechanisms, and for immunological interactions between hookworm infection and other diseases.Entities:
Mesh:
Year: 2004 PMID: 15771680 DOI: 10.1111/j.0141-9838.2004.00727.x
Source DB: PubMed Journal: Parasite Immunol ISSN: 0141-9838 Impact factor: 2.280