Literature DB >> 15771411

From 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk](1,4)benzodiazepin-2(1H)-one (TIBO) to etravirine (TMC125): fifteen years of research on non-nucleoside inhibitors of HIV-1 reverse transcriptase.

Bart L De Corte1.   

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Year:  2005        PMID: 15771411     DOI: 10.1021/jm040127p

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  21 in total

1.  Diarylaniline derivatives as a distinct class of HIV-1 non-nucleoside reverse transcriptase inhibitors.

Authors:  Bingjie Qin; Xingkai Jiang; Hong Lu; Xingtao Tian; Florent Barbault; Li Huang; Keduo Qian; Chin-Ho Chen; Rong Huang; Shibo Jiang; Kuo-Hsiung Lee; Lan Xie
Journal:  J Med Chem       Date:  2010-07-08       Impact factor: 7.446

2.  A novel nonnucleoside analogue that inhibits human immunodeficiency virus type 1 isolates resistant to current nonnucleoside reverse transcriptase inhibitors.

Authors:  Zhijun Zhang; Wen Xu; Yung-Hyo Koh; Jae Hoon Shim; Jean-Luc Girardet; Li-Tain Yeh; Robert K Hamatake; Zhi Hong
Journal:  Antimicrob Agents Chemother       Date:  2006-11-20       Impact factor: 5.191

3.  A ligand's-eye view of protein binding.

Authors:  Robert D Clark
Journal:  J Comput Aided Mol Des       Date:  2008-01-24       Impact factor: 3.686

4.  Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

Authors:  Xingtao Tian; Bingjie Qin; Zhiyuan Wu; Xiaofeng Wang; Hong Lu; Susan L Morris-Natschke; Chin Ho Chen; Shibo Jiang; Kuo-Hsiung Lee; Lan Xie
Journal:  J Med Chem       Date:  2010-11-04       Impact factor: 7.446

Review 5.  Impact of high-throughput screening in biomedical research.

Authors:  Ricardo Macarron; Martyn N Banks; Dejan Bojanic; David J Burns; Dragan A Cirovic; Tina Garyantes; Darren V S Green; Robert P Hertzberg; William P Janzen; Jeff W Paslay; Ulrich Schopfer; G Sitta Sittampalam
Journal:  Nat Rev Drug Discov       Date:  2011-03       Impact factor: 84.694

6.  Anti-human immunodeficiency activity of novel 2-arylpyrrolidine analogs.

Authors:  Ashot H Martirosyan; Sahak P Gasparyan; Marina V Alexanyan; Gohar K Harutyunyan; Henry A Panosyan; Raymond F Schinazi
Journal:  Med Chem Res       Date:  2016-10-17       Impact factor: 1.965

7.  Discovery of diarylpyridine derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Authors:  Xingtao Tian; Bingjie Qin; Hong Lu; Weihong Lai; Shibo Jiang; Kuo-Hsiung Lee; Chin Ho Chen; Lan Xie
Journal:  Bioorg Med Chem Lett       Date:  2009-07-19       Impact factor: 2.823

8.  Adult combination antiretroviral therapy in sub-Saharan Africa: lessons from Botswana and future challenges.

Authors:  C William Wester; Hermann Bussmann; John Koethe; Claire Moffat; Sten Vermund; Max Essex; Richard G Marlink
Journal:  HIV Ther       Date:  2009-09-01

9.  The "Connection" Between HIV Drug Resistance and RNase H.

Authors:  Krista A Delviks-Frankenberry; Galina N Nikolenko; Vinay K Pathak
Journal:  Viruses       Date:  2010-07-01       Impact factor: 5.048

10.  Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates.

Authors:  Lian-Qi Sun; Lei Zhu; Keduo Qian; Bingjie Qin; Li Huang; Chin Ho Chen; Kuo-Hsiung Lee; Lan Xie
Journal:  J Med Chem       Date:  2012-08-10       Impact factor: 7.446

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