Literature DB >> 15766776

RecX is involved in antioxidant mechanisms of the radioresistant bacterium Deinococcus radiodurans.

Duohong Sheng1, Guanjun Gao, Bing Tian, Zhenjian Xu, Zhiguo Zheng, Yuejin Hua.   

Abstract

Deinococcus radiodurans shows remarkable resistance to reactive oxygen species (ROS), generated by irradiation. Disruption of recX (dr1310) in D. radiodurans using targeted mutagenesis method enhanced its ROS scavenging activity, and recX overexpression in this bacterium repressed its antioxidant activity significantly. Further analyses on catalase and superoxide dismutase, two important antioxidant proteins in cells, showed that RecX could repress the induction of antioxidant enzymes, revealing that it negatively regulates the ROS scavenging activity in D. radiodurans.

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Year:  2005        PMID： 15766776     DOI： 10.1016/j.femsle.2005.01.051

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  7 in total

1.  Neisseria gonorrhoeae DNA recombination and repair enzymes protect against oxidative damage caused by hydrogen peroxide.

Authors:  Elizabeth A Stohl; H Steven Seifert
Journal:  J Bacteriol       Date:  2006-08-25       Impact factor: 3.490

Review 2.  Oxidative stress resistance in Deinococcus radiodurans.

Authors:  Dea Slade; Miroslav Radman
Journal:  Microbiol Mol Biol Rev       Date:  2011-03       Impact factor: 11.056

3.  DRA0336, another OxyR homolog, involved in the antioxidation mechanisms in Deinococcus radiodurans.

Authors:  Longfei Yin; Liangyan Wang; Huiming Lu; Guangzhi Xu; Huan Chen; Hongdan Zhan; Bing Tian; Yuejin Hua
Journal:  J Microbiol       Date:  2010-08-20       Impact factor: 3.422

4.  DrwH, a novel WHy domain-containing hydrophobic LEA5C protein from Deinococcus radiodurans, protects enzymatic activity under oxidative stress.

Authors:  Shijie Jiang; Jin Wang; Xiaoli Liu; Yingying Liu; Cui Guo; Liwen Zhang; Jiahui Han; Xiaoli Wu; Dong Xue; Ahmed E Gomaa; Shuai Feng; Heng Zhang; Yun Chen; Shuzhen Ping; Ming Chen; Wei Zhang; Liang Li; Zhengfu Zhou; Kaijing Zuo; Xufeng Li; Yi Yang; Min Lin
Journal:  Sci Rep       Date:  2017-08-24       Impact factor: 4.379

5.  Targeting Hsp20 Using the Novel Small Non-coding RNA DnrH Regulates Heat Tolerance in Deinococcus radiodurans.

Authors:  Dong Xue; Yun Chen; Jiang Li; Jiahui Han; Yingying Liu; Shijie Jiang; Zhengfu Zhou; Wei Zhang; Ming Chen; Min Lin; Marc Ongena; Jin Wang
Journal:  Front Microbiol       Date:  2019-10-11       Impact factor: 5.640

6.  A Novel Noncoding RNA dsr11 Involved in Heat Stress Tolerance in Deinococcus radiodurans.

Authors:  Dong Xue; Yun Chen; Jiang Li; Jiahui Han; Zhengfu Zhou; Wei Zhang; Ming Chen; Min Lin; Marc Ongena; Jin Wang
Journal:  Biomolecules       Date:  2019-12-23

7.  RNA-Seq-Based Comparative Transcriptome Analysis Highlights New Features of the Heat-Stress Response in the Extremophilic Bacterium Deinococcus radiodurans.

Authors:  Dong Xue; Wenzheng Liu; Yun Chen; Yingying Liu; Jiahui Han; Xiuxiu Geng; Jiang Li; Shijie Jiang; Zhengfu Zhou; Wei Zhang; Ming Chen; Min Lin; Marc Ongena; Jin Wang
Journal:  Int J Mol Sci       Date:  2019-11-09       Impact factor: 5.923
  7 in total

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