Literature DB >> 1575893

A computer model of cellular interactions in the immune system.

F Celada1, P E Seiden.   

Abstract

The power of modern computers allows the modeling and simulation of complex biological systems. The last decade has seen the emergence of a growing number of simulations of the immune system. In this article, Franco Celada and Philip Seiden present a model that, they suggest, is rich enough to allow computer experiments to be used as practical adjuncts to the usual biological experiments, at a saving of cost and time.

Mesh：

Year:  1992        PMID： 1575893     DOI： 10.1016/0167-5699(92)90135-T

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  48 in total

1.  Computer-modeling origin of a simple genetic apparatus.

Authors:  C Kuhn
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-17       Impact factor: 11.205

Review 2.  Computer simulations of heterologous immunity: highlights of an interdisciplinary cooperation.

Authors:  Claudia Calcagno; Roberto Puzone; Yanthe E Pearson; Yiming Cheng; Dario Ghersi; Liisa K Selin; Raymond M Welsh; Franco Celada
Journal:  Autoimmunity       Date:  2011-01-27       Impact factor: 2.815

Review 3.  Systems immunology: a survey of modeling formalisms, applications and simulation tools.

Authors:  Vipin Narang; James Decraene; Shek-Yoon Wong; Bindu S Aiswarya; Andrew R Wasem; Shiang Rong Leong; Alexandre Gouaillard
Journal:  Immunol Res       Date:  2012-09       Impact factor: 2.829

Review 4.  Systems biology in immunology: a computational modeling perspective.

Authors:  Ronald N Germain; Martin Meier-Schellersheim; Aleksandra Nita-Lazar; Iain D C Fraser
Journal:  Annu Rev Immunol       Date:  2011       Impact factor: 28.527

5.  A coherent framework for multiresolution analysis of biological networks with "memory": Ras pathway, cell cycle, and immune system.

Authors:  Paolo Emilio Barbano; Marina Spivak; Jiawu Feng; Marco Antoniotti; Bud Mishra
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-20       Impact factor: 11.205

6.  Narrowed TCR repertoire and viral escape as a consequence of heterologous immunity.

Authors:  Markus Cornberg; Alex T Chen; Lee A Wilkinson; Michael A Brehm; Sung-Kwon Kim; Claudia Calcagno; Dario Ghersi; Roberto Puzone; Franco Celada; Raymond M Welsh; Liisa K Selin
Journal:  J Clin Invest       Date:  2006-04-13       Impact factor: 14.808

7.  A discrete computer model of the immune system reveals competitive interactions between the humoral and cellular branch and between cross-reacting memory and naïve responses.

Authors:  Yiming Cheng; Dario Ghersi; Claudia Calcagno; Liisa K Selin; Roberto Puzone; Franco Celada
Journal:  Vaccine       Date:  2008-12-25       Impact factor: 3.641

8.  Biological implication for loss of function at major histocompatibility complex loci.

Authors:  Hiromi Sawai; Yasuhiro Go; Yoko Satta
Journal:  Immunogenetics       Date:  2008-05-07       Impact factor: 2.846

Review 9.  At the biological modeling and simulation frontier.

Authors:  C Anthony Hunt; Glen E P Ropella; Tai Ning Lam; Jonathan Tang; Sean H J Kim; Jesse A Engelberg; Shahab Sheikh-Bahaei
Journal:  Pharm Res       Date:  2009-09-09       Impact factor: 4.200

10.  Predicting the size of the T-cell receptor and antibody combining region from consideration of efficient self-nonself discrimination.

Authors:  J K Percus; O E Percus; A S Perelson
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-01       Impact factor: 11.205
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