Literature DB >> 15752625

Simultaneous determination of six isoflavonoids in commercial Radix Astragali by HPLC-UV.

Tao Wu1, S W Annie Bligh, Li-hua Gu, Zheng-tao Wang, He-ping Liu, Xue-mei Cheng, Chris J Branford-White, Zhi-bi Hu.   

Abstract

A HPLC-UV method for the quantification of six major isoflavonoids, calycosin 7-O-beta-D-glucoside (1), formononetin 7-O-beta-D-glucoside (2), (6alphaR, 11alphaR) 3-hydroxy-9,10-dimethoxypterocarpan-3-O-beta-D-glucoside (3), 7,2'-dihydroxy-3',4'-dimethoxyisoflavan-7-O-beta-D-glucoside (4), calycosin (5) and formononetin (6), in Radix Astragali (Huangqi) was developed and validated. The method was proven to be sensitive, specific, accurate and precise, as well as effective and easy.

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Year:  2005        PMID: 15752625     DOI: 10.1016/j.fitote.2004.11.006

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  13 in total

1.  Accumulation of calycosin and its 7-O-beta-D-glucoside and related gene expression in seedlings of Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao induced by low temperature stress.

Authors:  Haiyun Pan; Changming Fang; Tongshui Zhou; Qingzhong Wang; Jiakuan Chen
Journal:  Plant Cell Rep       Date:  2007-01-26       Impact factor: 4.570

2.  Comparison of the immunoregulatory function of different constituents in radix astragali and radix hedysari.

Authors:  Jing Liu; Xuguang Hu; Quan Yang; Zhiling Yu; Zhongzhen Zhao; Tao Yi; Hubiao Chen
Journal:  J Biomed Biotechnol       Date:  2010-03-09

3.  Global transcriptome analysis profiles metabolic pathways in traditional herb Astragalus membranaceus Bge. var. mongolicus (Bge.) Hsiao.

Authors:  Jing Chen; Xue-Ting Wu; Yi-Qin Xu; Yang Zhong; Yi-Xue Li; Jia-Kuan Chen; Xuan Li; Peng Nan
Journal:  BMC Genomics       Date:  2015-06-11       Impact factor: 3.969

4.  Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca2+-Activated K+ Channels (BKCa).

Authors:  Hisa Hui Ling Tseng; Chi Teng Vong; George Pak-Heng Leung; Sai Wang Seto; Yiu Wa Kwan; Simon Ming-Yuen Lee; Maggie Pui Man Hoi
Journal:  Evid Based Complement Alternat Med       Date:  2016-11-23       Impact factor: 2.629

5.  Quantification of six bioactive compounds in Zhenqi Fuzheng preparation by high-performance liquid chromatography coupled with diode array detector and evaporative light scattering detector.

Authors:  Yi-Kai Shi; Fang Cui; Fang-Di Hu; Ying-Yan Bi; Yu-Feng Ma; Shi-Lan Feng
Journal:  J Pharm Anal       Date:  2012-01-30

6.  HPLC-DAD-ELSD Combined Pharmacodynamics and Serum Medicinal Chemistry for Quality Assessment of Huangqi Granule.

Authors:  Huaguo Chen; Xin Zhou; Yang Zhao; Xiao-Jian Gong; Yan He; Feng-Wei Ma; Mei Zhou; Chao Zhao; Yi Niu; Jie Deng
Journal:  PLoS One       Date:  2015-04-27       Impact factor: 3.240

7.  Isoflavone production in Cyclopia subternata Vogel (honeybush) suspension cultures grown in shake flasks and stirred-tank bioreactor.

Authors:  Adam Kokotkiewicz; Maria Luczkiewicz; Wiktor Kowalski; Anna Badura; Natalia Piekus; Adam Bucinski
Journal:  Appl Microbiol Biotechnol       Date:  2013-07-20       Impact factor: 4.813

8.  Simultaneous determination of six active metabolites in Astragalus mongholicus (Fisch.) Bge. under salt stress by ultra-pressure liquid chromatography with tandem mass spectrometry.

Authors:  Yang Liu; Jia Liu; Yu Wang; Ann Abozeid; Zhong-Hua Tang
Journal:  Springerplus       Date:  2016-06-30

9.  System Pharmacology-Based Dissection of the Synergistic Mechanism of Huangqi and Huanglian for Diabetes Mellitus.

Authors:  Shi-Jun Yue; Juan Liu; Wu-Wen Feng; Fei-Long Zhang; Jian-Xin Chen; Lan-Ting Xin; Cheng Peng; Hua-Shi Guan; Chang-Yun Wang; Dan Yan
Journal:  Front Pharmacol       Date:  2017-10-05       Impact factor: 5.810

10.  UV-B Radiation Largely Promoted the Transformation of Primary Metabolites to Phenols in Astragalus mongholicus Seedlings.

Authors:  Yang Liu; Jia Liu; Ann Abozeid; Ke-Xin Wu; Xiao-Rui Guo; Li-Qiang Mu; Zhong-Hua Tang
Journal:  Biomolecules       Date:  2020-03-26
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