BACKGROUND: Diffusion is a physical process based on the random movement of water molecules known as Brownian movement. Diffusion-weighted imaging (DWI) is a magnetic resonance (MR) technique that provides information about the biophysical properties of tissues such cell organization and density, microstructure and microcirculation. MATERIALS AND METHODS: Twenty healthy volunteers and 18 patients with renal tumor were enrolled in our study. The DWI was obtained before contrast media injection with a single-shot SE EPI Inversion Recovery (IR) sequence. The tumor cellularity of each resected lesion was evaluated. RESULTS: The mean apparent diffusion coefficient (ADC) value of renal tumors was significantly lower than the mean ADC value of normal renal parenchyma. In our series, the mean ADC value of renal tumors did not significantly correlate with tumor cellularity, but correlated with histological architecture. CONCLUSION: These preliminary results indicate the utility of DWI in the acquisition of tissue characterization data of renal masses using a minimal acquisition time (17 sec).
BACKGROUND: Diffusion is a physical process based on the random movement of water molecules known as Brownian movement. Diffusion-weighted imaging (DWI) is a magnetic resonance (MR) technique that provides information about the biophysical properties of tissues such cell organization and density, microstructure and microcirculation. MATERIALS AND METHODS: Twenty healthy volunteers and 18 patients with renal tumor were enrolled in our study. The DWI was obtained before contrast media injection with a single-shot SE EPI Inversion Recovery (IR) sequence. The tumor cellularity of each resected lesion was evaluated. RESULTS: The mean apparent diffusion coefficient (ADC) value of renal tumors was significantly lower than the mean ADC value of normal renal parenchyma. In our series, the mean ADC value of renal tumors did not significantly correlate with tumor cellularity, but correlated with histological architecture. CONCLUSION: These preliminary results indicate the utility of DWI in the acquisition of tissue characterization data of renal masses using a minimal acquisition time (17 sec).
Authors: Junzhong Xu; Xiaoyu Jiang; Hua Li; Lori R Arlinghaus; Eliot T McKinley; Sean P Devan; Benjamin M Hardy; Jingping Xie; Hakmook Kang; A Bapsi Chakravarthy; John C Gore Journal: Magn Reson Med Date: 2019-11-25 Impact factor: 4.668
Authors: E E Sigmund; G Y Cho; S Kim; M Finn; M Moccaldi; J H Jensen; D K Sodickson; J D Goldberg; S Formenti; L Moy Journal: Magn Reson Med Date: 2011-02-01 Impact factor: 4.668
Authors: Maria A Bedoya; Jeffrey I Berman; Jorge Delgado; Dmitry Khrichenko; Christian A Barrera; Robert H Carson; Kassa Darge Journal: Pediatr Radiol Date: 2019-04-19
Authors: G Manenti; M Di Roma; S Mancino; D A Bartolucci; G Palmieri; R Mastrangeli; R Miano; E Squillaci; G Simonetti Journal: Radiol Med Date: 2008-04-02 Impact factor: 3.469
Authors: Anwar R Padhani; Guoying Liu; Dow Mu Koh; Thomas L Chenevert; Harriet C Thoeny; Taro Takahara; Andrew Dzik-Jurasz; Brian D Ross; Marc Van Cauteren; David Collins; Dima A Hammoud; Gordon J S Rustin; Bachir Taouli; Peter L Choyke Journal: Neoplasia Date: 2009-02 Impact factor: 5.715