Literature DB >> 15731094

Glutathione and nitrosoglutathione in macrophage defense against Mycobacterium tuberculosis.

Vishwanath Venketaraman1, Yaswant K Dayaram, Meliza T Talaue, Nancy D Connell.   

Abstract

We demonstrate that Mycobacterium tuberculosis grown in vitro is sensitive to glutathione and its derivative S-nitrosoglutathione. Furthermore, our infection studies with J774.1 macrophages indicate that glutathione is essential for the control of the intracellular growth of M. tuberculosis. This study indicates the important role of glutathione in the control of macrophages by M. tuberculosis.

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Year:  2005        PMID: 15731094      PMCID: PMC1064956          DOI: 10.1128/IAI.73.3.1886-1889.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  15 in total

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Authors:  E D Chan; J Chan; N W Schluger
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2.  Comparison of the roles of reactive oxygen and nitrogen intermediates in the host response to Mycobacterium tuberculosis using transgenic mice.

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3.  Toxicity of nitrogen oxides and related oxidants on mycobacteria: M. tuberculosis is resistant to peroxynitrite anion.

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Journal:  Tuber Lung Dis       Date:  1999

4.  Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice.

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Journal:  Immunity       Date:  1995-06       Impact factor: 31.745

5.  Glutathione: is it an evolutionary vestige of the penicillins?

Authors:  J E Spallholz
Journal:  Med Hypotheses       Date:  1987-07       Impact factor: 1.538

6.  Antibacterial effect of cysteine-nitrosothiol and possible percursors thereof.

Authors:  K Incze; J Farkas; V Mihályi; E Zukál
Journal:  Appl Microbiol       Date:  1974-01

Review 7.  Tuberculosis: commentary on a reemergent killer.

Authors:  B R Bloom; C J Murray
Journal:  Science       Date:  1992-08-21       Impact factor: 47.728

8.  Role of glutathione in macrophage control of mycobacteria.

Authors:  Vishwanath Venketaraman; Yaswant K Dayaram; Amol G Amin; Richard Ngo; Renee M Green; Meliza T Talaue; Jessica Mann; Nancy D Connell
Journal:  Infect Immun       Date:  2003-04       Impact factor: 3.441

9.  Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages.

Authors:  J Chan; Y Xing; R S Magliozzo; B R Bloom
Journal:  J Exp Med       Date:  1992-04-01       Impact factor: 14.307

10.  An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.

Authors:  J L Flynn; J Chan; K J Triebold; D K Dalton; T A Stewart; B R Bloom
Journal:  J Exp Med       Date:  1993-12-01       Impact factor: 14.307

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  41 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-08       Impact factor: 11.205

2.  The mycobacterial transcriptional regulator whiB7 gene links redox homeostasis and intrinsic antibiotic resistance.

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Review 3.  Are reactive oxygen species always detrimental to pathogens?

Authors:  Claudia N Paiva; Marcelo T Bozza
Journal:  Antioxid Redox Signal       Date:  2013-10-26       Impact factor: 8.401

Review 4.  New targets and inhibitors of mycobacterial sulfur metabolism.

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Journal:  Infect Disord Drug Targets       Date:  2013-04

5.  Control of Mycobacterium tuberculosis growth by activated natural killer cells.

Authors:  C Guerra; K Johal; D Morris; S Moreno; O Alvarado; D Gray; M Tanzil; D Pearce; V Venketaraman
Journal:  Clin Exp Immunol       Date:  2012-04       Impact factor: 4.330

6.  WhiB5, a transcriptional regulator that contributes to Mycobacterium tuberculosis virulence and reactivation.

Authors:  Stefano Casonato; Axel Cervantes Sánchez; Hirohito Haruki; Monica Rengifo González; Roberta Provvedi; Elisa Dainese; Thomas Jaouen; Susanne Gola; Estela Bini; Miguel Vicente; Kai Johnsson; Daniela Ghisotti; Giorgio Palù; Rogelio Hernández-Pando; Riccardo Manganelli
Journal:  Infect Immun       Date:  2012-06-25       Impact factor: 3.441

7.  S-nitrosomycothiol reductase and mycothiol are required for survival under aldehyde stress and biofilm formation in Mycobacterium smegmatis.

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Journal:  IUBMB Life       Date:  2016-06-19       Impact factor: 3.885

8.  Direct EPR Detection of Nitric Oxide in Mice Infected with the Pathogenic Mycobacterium Mycobacterium tuberculosis.

Authors:  Anatoly F Vanin; Raisa P Selitskaya; Vladimir A Serezhenkov; Galina N Mozhokina
Journal:  Appl Magn Reson       Date:  2009-12-03       Impact factor: 0.831

Review 9.  Drug targets in mycobacterial sulfur metabolism.

Authors:  Devayani P Bhave; Wilson B Muse; Kate S Carroll
Journal:  Infect Disord Drug Targets       Date:  2007-06

Review 10.  Cell-autonomous effector mechanisms against mycobacterium tuberculosis.

Authors:  John D MacMicking
Journal:  Cold Spring Harb Perspect Med       Date:  2014-07-31       Impact factor: 6.915

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