Literature DB >> 15728941

Susceptibility of Streptococcus mutans and Actinobacillus actinomycetemcomitans to bactericidal activity of human beta-defensin 3 in biological fluids.

Giuseppantonio Maisetta1, Giovanna Batoni, Semih Esin, Giorgio Raco, Daria Bottai, Flavia Favilli, Walter Florio, Mario Campa.   

Abstract

Bactericidal activity of human beta-defensin 3 (hBD-3) against Streptococcus mutans and Actinobacillus actinomycetemcomitans was inhibited in a dose-dependent manner by the presence of saliva and/or serum. Increasing the concentration of hBD-3 partially overcame this inhibition. A fast bactericidal effect was observed against both bacterial strains, suggesting a potential therapeutic use for hBD-3 in the local treatment of oral infections.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 15728941      PMCID： PMC549272          DOI： 10.1128/AAC.49.3.1245-1248.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

Review 1.  Cationic peptides: effectors in innate immunity and novel antimicrobials.

Authors:  R E Hancock
Journal:  Lancet Infect Dis       Date:  2001-10       Impact factor: 25.071

2.  Expression of beta-defensins in gingival health and in periodontal disease.

Authors:  John Bissell; Sophie Joly; Georgia K Johnson; Connie C Organ; Deborah Dawson; Paul B McCray; Janet M Guthmiller
Journal:  J Oral Pathol Med       Date:  2004-05       Impact factor: 4.253

Review 3.  Defensins: antimicrobial peptides of innate immunity.

Authors:  Tomas Ganz
Journal:  Nat Rev Immunol       Date:  2003-09       Impact factor: 53.106

4.  Sensitivity of Actinobacillus actinomycetemcomitans and Capnocytophaga spp. to the bactericidal action of LL-37: a cathelicidin found in human leukocytes and epithelium.

Authors:  D Tanaka; K T Miyasaki; R I Lehrer
Journal:  Oral Microbiol Immunol       Date:  2000-08

5.  First characterization in Italy of clinical isolates of mutans streptococci by using specific monoclonal antibodies.

Authors:  G Batoni; F Marchetti; F Ota; E Ghelardi; S Barnini; H Inoue; C Uchiyama; K Hirota; Y Minato; M R Guica
Journal:  Eur J Epidemiol       Date:  1993-09       Impact factor: 8.082

6.  Activated alpha 2-macroglobulin is a principal defensin-binding protein.

Authors:  A Panyutich; T Ganz
Journal:  Am J Respir Cell Mol Biol       Date:  1991-08       Impact factor: 6.914

7.  IB-367, a protegrin peptide with in vitro and in vivo activities against the microflora associated with oral mucositis.

Authors:  D A Mosca; M A Hurst; W So; B S Viajar; C A Fujii; T J Falla
Journal:  Antimicrob Agents Chemother       Date:  2000-07       Impact factor: 5.191

8.  Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic.

Authors:  J Harder; J Bartels; E Christophers; J M Schroder
Journal:  J Biol Chem       Date:  2000-11-20       Impact factor: 5.157

9.  Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms.

Authors:  Sophie Joly; Connie Maze; Paul B McCray; Janet M Guthmiller
Journal:  J Clin Microbiol       Date:  2004-03       Impact factor: 5.948

10.  Apolipoprotein A-I binds and inhibits the human antibacterial/cytotoxic peptide LL-37.

Authors:  Y Wang; B Agerberth; A Löthgren; A Almstedt; J Johansson
Journal:  J Biol Chem       Date:  1998-12-11       Impact factor: 5.157
View more
  6 in total

1.  In vitro bactericidal activity of human beta-defensin 3 against multidrug-resistant nosocomial strains.

Authors:  Giuseppantonio Maisetta; Giovanna Batoni; Semih Esin; Walter Florio; Daria Bottai; Flavia Favilli; Mario Campa
Journal:  Antimicrob Agents Chemother       Date:  2006-02       Impact factor: 5.191

2.  Effects of a derivative of reutericin 6 and gassericin A on the biofilm of Streptococcus mutans in vitro and caries prevention in vivo.

Authors:  Jingheng Liang; Dongsheng Liang; Yuee Liang; Jianing He; Shiya Zuo; Wanghong Zhao
Journal:  Odontology       Date:  2020-05-30       Impact factor: 2.634

3.  Novel synthetic, salt-resistant analogs of human beta-defensins 1 and 3 endowed with enhanced antimicrobial activity.

Authors:  Olga Scudiero; Stefania Galdiero; Marco Cantisani; Rosa Di Noto; Mariateresa Vitiello; Massimiliano Galdiero; Gino Naclerio; Jean-Jacques Cassiman; Carlo Pedone; Giuseppe Castaldo; Francesco Salvatore
Journal:  Antimicrob Agents Chemother       Date:  2010-03-22       Impact factor: 5.191

4.  Human beta-defensins kill Candida albicans in an energy-dependent and salt-sensitive manner without causing membrane disruption.

Authors:  Slavena Vylkova; Namrata Nayyar; Wansheng Li; Mira Edgerton
Journal:  Antimicrob Agents Chemother       Date:  2006-10-30       Impact factor: 5.191

5.  The Opp (AmiACDEF) Oligopeptide Transporter Mediates Resistance of Serotype 2 Streptococcus pneumoniae D39 to Killing by Chemokine CXCL10 and Other Antimicrobial Peptides.

Authors:  Kevin E Bruce; Britta E Rued; Ho-Ching Tiffany Tsui; Malcolm E Winkler
Journal:  J Bacteriol       Date:  2018-05-09       Impact factor: 3.490

Review 6.  Role of beta-defensins in oral epithelial health and disease.

Authors:  Yoshihiro Abiko; Masto Saitoh; Michiko Nishimura; Mami Yamazaki; Daisuke Sawamura; Tohru Kaku
Journal:  Med Mol Morphol       Date:  2007-12-21       Impact factor: 2.309
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.