Literature DB >> 15728940

Experimental prediction of the evolution of ceftazidime resistance in the CTX-M-2 extended-spectrum beta-lactamase.

Kerry J Welsh1, Miriam Barlow, Fred C Tenover, James W Biddle, J Kamile Rasheed, Leigh Ann Clark, John E McGowan.   

Abstract

We applied in vitro evolution to an Escherichia coli strain containing bla(CTX-M-2) and obtained 10 independent mutant bla(CTX-M-2) alleles that confer elevated resistance to ceftazidime (MIC > or = 32 microg/ml) but lost the ability to confer resistance to cefepime. All alleles had a Pro-to-Ser substitution at position 167.

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Year:  2005        PMID： 15728940      PMCID： PMC549256          DOI： 10.1128/AAC.49.3.1242-1244.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  14 in total

Review 1.  New beta-lactamases in gram-negative bacteria: diversity and impact on the selection of antimicrobial therapy.

Authors:  K Bush
Journal:  Clin Infect Dis       Date:  2001-03-21       Impact factor: 9.079

2.  CTX-M-type beta-lactamases: an emerging group of extended-spectrum enzymes.

Authors:  L S Tzouvelekis; E Tzelepi; P T Tassios; N J Legakis
Journal:  Int J Antimicrob Agents       Date:  2000-03       Impact factor: 5.283

3.  Predicting evolutionary potential: in vitro evolution accurately reproduces natural evolution of the tem beta-lactamase.

Authors:  Miriam Barlow; Barry G Hall
Journal:  Genetics       Date:  2002-03       Impact factor: 4.562

4.  Biochemical analysis of the ceftazidime-hydrolysing extended-spectrum beta-lactamase CTX-M-15 and of its structurally related beta-lactamase CTX-M-3.

Authors:  Laurent Poirel; Marek Gniadkowski; Patrice Nordmann
Journal:  J Antimicrob Chemother       Date:  2002-12       Impact factor: 5.790

Review 5.  Growing group of extended-spectrum beta-lactamases: the CTX-M enzymes.

Authors:  R Bonnet
Journal:  Antimicrob Agents Chemother       Date:  2004-01       Impact factor: 5.191

6.  Experimental prediction of the evolution of cefepime resistance from the CMY-2 AmpC beta-lactamase.

Authors:  Miriam Barlow; Barry G Hall
Journal:  Genetics       Date:  2003-05       Impact factor: 4.562

7.  A standard numbering scheme for the class A beta-lactamases.

Authors:  R P Ambler; A F Coulson; J M Frère; J M Ghuysen; B Joris; M Forsman; R C Levesque; G Tiraby; S G Waley
Journal:  Biochem J       Date:  1991-05-15       Impact factor: 3.857

8.  CTX-M-type extended-spectrum beta-lactamase that hydrolyzes ceftazidime through a single amino acid substitution in the omega loop.

Authors:  L Poirel; T Naas; I Le Thomas; A Karim; E Bingen; P Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2001-12       Impact factor: 5.191

9.  Extended-spectrum beta-lactamases in enterobacteriaceae in Buenos Aires, Argentina, public hospitals.

Authors:  M Quinteros; M Radice; N Gardella; M M Rodriguez; N Costa; D Korbenfeld; E Couto; G Gutkind
Journal:  Antimicrob Agents Chemother       Date:  2003-09       Impact factor: 5.191

10.  Cefepime MIC as a predictor of the extended-spectrum beta-lactamase type in Klebsiella pneumoniae, Taiwan.

Authors:  Wen Liang Yu; Michael A Pfaller; Patricia L Winokur; Ronald N Jones
Journal:  Emerg Infect Dis       Date:  2002-05       Impact factor: 6.883
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  5 in total

1.  CTX-M expression and selection of ertapenem resistance in Klebsiella pneumoniae and Escherichia coli.

Authors:  Delphine Girlich; Laurent Poirel; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2008-11-24       Impact factor: 5.191

2.  The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M β-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation.

Authors:  Meha P Patel; Liya Hu; Vlatko Stojanoski; Banumathi Sankaran; B V Venkataram Prasad; Timothy Palzkill
Journal:  Biochemistry       Date:  2017-06-27       Impact factor: 3.162

3.  Mutational events in cefotaximase extended-spectrum beta-lactamases of the CTX-M-1 cluster involved in ceftazidime resistance.

Authors:  Angela Novais; Rafael Cantón; Teresa M Coque; Andrés Moya; Fernando Baquero; Juan Carlos Galán
Journal:  Antimicrob Agents Chemother       Date:  2008-04-28       Impact factor: 5.191

4.  CTX-M-35 extended-spectrum beta-lactamase conferring ceftazidime resistance in Citrobacter koseri.

Authors:  Guo-Bao Tian; Jennifer M Adams-Haduch; Zubair A Qureshi; Hong-Ning Wang; Yohei Doi
Journal:  Int J Antimicrob Agents       Date:  2010-04       Impact factor: 5.283

5.  Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains.

Authors:  Marina N Stepanova; Maxim Pimkin; Anatoly A Nikulin; Varvara K Kozyreva; Elena D Agapova; Mikhail V Edelstein
Journal:  Antimicrob Agents Chemother       Date:  2008-01-22       Impact factor: 5.191
  5 in total

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